3599 results
Focusing on disease-modifying rather than etiologic mechanisms may accelerate the development of novel therapies and complement current research initiatives on causative mechanisms and curative therapies.
Education on guidelines, combined with quality targets within the accreditation procedure improves quality of antibiotic prescribing
The expected sensitivity of the CardioWatch 287 is 95%, as compared to the classical resting ECG recording. Sensitivity is defined as the percentage of HR and RR-intervals detected by the smartwatch, matching with the resting ECG recording.
Office endometrial sampling is not suitable to diagnose EIN due to the small amount of tissue obtained.
Different prevention strategies are used internationally to prevent Early-onset Group B haemolytic streptococcus infection (EOGBS). However, none of the preventive EOGBS strategies in place at present result in the complete prevention of EOGBS,…
Current clinical practice is to perform response evaluation, i.e. examination under general anesthesia (EUA), routinely at 3 months after the end of treatment in patients who underwent chemoradiation for oropharyngeal cancer. Due the high response…
COMT and/or PRODH polymorphisms are debt to cognitive deterioration in velocardiofacial syndrome.
We postulate that exhaled molecular profiling obtained from ‘breathprints’ by electronic nose: 1. Is associated with the level of asthma control and; 2. Is associated with an inflammatory profile in induced sputum and blood in steroiddependent…
Muscle hypoxia, either chronic or intermittent (exercise-induced), is responsible for the altered muscle oxidative phenotype in chronic obstructive pulmonary disease and chronic heart failure through modulation of the regulatory molecules PGC-1/…
Antireflux surgery is one of the most common major operations performed in pediatric patients. Most studies on the outcome of antireflux surgery in children are limited to retrospective data, case reports or are based solely on symptoms. A…
Submucous fibroids are known to be related to heavy menstrual bleeding (HMB), dysmenorrhea and fertility problems. Transcervical resection of fibroids (TCRM) is a widely implemented treatment for submucous fibroids, to be precise FIGO PALM-COEIN…
The purpose of the study is to evaluate the outcomes and midterm follow-up in the mini-gastric bypass in terms of weight loss, resolution of co-morbidities and the impact of different BP-limb lengths.
Obesity is a growing world wide problem. In The Netherlands, about 10% of all men and women have a BMI of 30 kg/m2 or more. Obesity is a chronic, uncurable metabolic disorder, which is characterised by excessive fatstorage at unfavorable places.…
We hypothesize that group medical appointments will enhance adherence to treatment and self-efficacy in patients with sickle cell disease, as well as increase quality of life, and satisfaction with the treating physician and nurse. When performing…
Kidney transplantation is the only treatment offering long-term benefit to patients with chronic kidney failure. Urological complications after kidney transplantation, such as urinary leakage and ureteral strictures, are associated with significant…
Health outcomes for people at risk of or suffering from non-communicable lung diseases in low-resource settings will be improved by developing capacity for implementation of evidence-based interventions for prevention, diagnosis and treatment in…
We expect that planned visits at the outpatient clinic are unnecessary due to low percentage of treatment changes. Furthermore, we expect that treatment changes will appear at unplanned visits.
The level of AGEs can predict response to intravitreal anti-VEGF therapy in DME
MPS I patients can be treated with Aldurazyme safely and effectively.
Patient education on extended anticoagulation pros and cons: a journey app in venous thromboembolism
Our hypothesis is that patients whom receive targeted information about VTE and (extended) anticoagulation treatment with the 'patient journey app' on a daily basis in the week preceding their hospital visit will be more satisfied with the…