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Wireless Micro Current Stimulation: adjunctive therapy for hard-to-heal chronic wounds * a double-blind, placebo controlled trial

Our aim is to determine whether Wireless Micro Current Stimulation accelerates wound healing in hard-to-heal chronic wounds as compared to standard wound care treatment by conducting a double-blind, placebo controlled trial.

Effect of infrapatellar nerve block on chronic anterior knee pain after tibial nailing.

To study the effect of a nerve block of the infrapatellar nerve with local infiltration with lidocaine or saline on chronic anterior knee pain after tibial nailing.Secondairy objectives:- to measure knee pain on a VAS for eight different activities…

A phase II study of ARA 290 as therapeutic strategy in no-option critical limb ischemia patients.

A proof of concept study to test whether ARA 290 improves wound healing and reduces neuropathic pain in no-option patients with CLI

Efficacy of Arnica D1 ointment after upper blepharoplasty: a randomized, double-blind, placebo-controlled study

To evaluate the efficacy of Arnica om postoperative outcome after upper blepharoplasty.

The anterior cutaneus nerve entrapment syndrome (ACNES). Randomized double blind controlled trial for the diagnosis and treatment of entrapment of the anterior cutaneus nerve through the rectus muscle.

Evaluation of the effect ofdiagnostic and therapeutic proces in reducing pain in patients suspected with ACNES.Is injection of lidocaine in patients suspected of ACNES leading to a larger group of people with a clinically relevant reduction of pain…

Effectiveness and cost-effectiveness of lymphaticovenous anastomosis for cancer patients who suffer from chronic peripheral lymphedema

Primary Objective:The primary objective is to assess the efficacy of LVA surgery in comparison to sham procedure in patients with cancer related lymphedema in the context of improvement of Lymph-ICF score at 12 and 24 months follow up. Secondary…

EPIK-P2: A Phase II double-blind study with an upfront, 16-week randomized, placebo-controlled period, to assess the efficacy, safety and pharmacokinetics of alpelisib (BYL719) in pediatric and adult patients with PIK3CA-related overgrowth spectrum (PROS)

This study has been transitioned to CTIS with ID 2023-508530-34-00 check the CTIS register for the current data. Primary objective:* To demonstrate the efficacy of alpelisib as measured by the proportion of participants randomized to alpelisib with…

Stromal Vascular Fraction injectable as a preventive treatment of scars.

To quantify clinical and histological improvements in prevention of scars when SVF injectable is used as treatment.

A Phase 4, Double-Blind, Randomized, Placebo-Controlled Multicenter Study to Assess the Safety and Efficacy of Adalimumab Used in Conjunction with Surgery in Subjects with Moderate to Severe Hidradenitis Suppurativa

Primary objective:Assess the safety and efficacy of adalimumab prior to surgery in subjects with moderate to severe HS who are surgical candidates.Secondary objectives:Assess the impact of adalimumab on the planned HS surgical site before surgery,…

CE marking for the Q-whet micro current wound stimulator

Objective:The objective of the study is to test the hypothesis that the QWHET micro current wound stimulation device has minimal side effects. The study will be designed as a double blind, prospective study.The results will be used to obtain a CE…

Stromal Vascular Fraction and Platelet-rich Plasma injectable to promote dermal wound healing.

To quantify clinical and histological changes of the skin in promoting early wound healing when SVF + PRP injectable is used as treatment in comparison to SVF and PRP alone.