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Efficacy of repetitive transcranial magnetic stimulation in patients with medication-resistant bipolar depression. A multicenter, randomized, double-blind, sham-controlled study

Objective: We want to determine the effectiveness of rTMS in patients with bipolar depression who did not respond to two or more adequately dosed medication trials, using an adequately powered pragmatic RCT. We hypothesize that active rTMS, compared…

Probiotic formulation for patients with schizophrenia or bipolar disorder who have screened positive for increased intestinal permeability
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The primary objective of this trial is to investigate the effects of probiotics, as compared to placebo, when given in addition to antipsychotic/mood stabilizing medication to a selected patient sample. Our aim will be to lower symptom severity as…

Effect of amiloride on polyuria and well being in lithium treated patients

Primary objective: to investigate the effect of amiloride on urine volume and urinary concentrating ability in patients on chronic lithium therapy suffering from polyuria.We hypothesize that amiloride therapy will improve urinary concentating…