31 results
The primary objective of the present study is to investigate the effect of the fat emulsion on energy intake at lunch.
To determine the safety and tolerability of P1201-07 administered as single ascending oral doses in overweight or obese but otherwise healthy subjects.
Primary objective1. To investigate whether TM38837 attenuates the central effects of THCSecondary objectives2. To explore the effect of TM38837 on THC induced effects on heart rate3. To investigate the effect of 60 mg rimonabant on THC-induced CNS…
To investigate the effect of low-dose long acting insulin therapy on nutritional status in adult CF patients without diabetes.
The primary objectives are: 1) to determine the effect of bile acids on glucose uptake in brown adipose tissue; 2) to determine the effect of bile acids on whole body energy expenditure and 3) to determine the effect of bile acids on skeletal muscle…
The primary objective of the study is to find the appropriate, clinically relevant dosages (among the 5, 10, and 15 mg twice-daily dosages) of JNJ-16269110 by assessing mean changes in body weight from baseline to Week 12, compared to placebo .The…
1) Examining actual changes in food intake and food preference for different foods following psychosocial laboratory-induced stress;2) Examining the effect of multiple (instead of single) dietary TRP administration on acute stress-induced (negative…
To investigate the long-term effects of green tea on gut flora, fat absorption, resting energy expenditure and body composition.
Primary ObjectiveTo determine whether moderate alcohol consumption influences subsequent food reward, as measured by questionnaires on food *wanting* and food *liking*, and salivary and blood parameters related to food reward.Secondary ObjectivesTo…
Based on the data available, Anamorelin HCl produces an increase in total body weight and Lean Body Mass in patients with advanced cancer, and specifically in patients with NSCLC, in addition to increasing muscle strength and improving quality of…
To establish the efficacy of 60 mg baclofen compared to placebo in inducing a decrease in food craving, as assessed by a food craving questionnaires (G-FCQ-T) over 6 months in obese subjects.
Based on the data available, Anamorelin HCl produces an increase in total body weight and Lean Body Mass in patients with advanced cancer, and specifically in patients with NSCLC, in addition to increasing muscle strength and improving quality of…
The objective of this project is to identify a well consumable butyrate/hexanoate-enriched oil that increase circulating SCFA levels and improves postprandial substrate metabolism. We will investigate the effects of acute intake of four different…
The aim is to see whether intradialytic parenteral nutrition is an efective treatment against the loss of muscle mass
We hypothesize that intragastric infusion of lidocaine will result in a delay of postprandial satiation and hereby an increase in food intake at an ad libitum meal. Furthermore, we hypothesize that lidocaine infusion will not result in an increase…
This study has been transitioned to CTIS with ID 2024-513570-22-00 check the CTIS register for the current data. This trial aims to investigate whether peroperative administration of TXA reduces haemorrhage rates in patients who undergo metabolic…
This trial aims to investigate if peroperative administration of TA can reduce the peroperative and postoperative hemorrhage rates in laparoscopic sleeve gastrectomy.
This Phase 2b/3 double-blind, placebo-controlled study will evaluate the safety, tolerability, and effects of livoletide on food-related behaviors in patients with Prader-Willi Syndrome (PWS).
Primary objective- To compare the efficacy of liraglutide versus placebo on weight loss in obese paediatric subjects with PWS at 16 weeks and versus no treatment at 52 weeks.Secondary objectives - To compare the efficacy of liraglutide versus…
The main purpose of this trial is to find out if an investigational drug called setmelanotide (RM-493), which mimics MSH, can help control body weight. The efficacy of setmelanotide will be compared to the efficacy of a placebo during 4 to 8 weeks.