356 results
Primary Objective: To compare the effects of hypothyroidism and hyperthyroidism on cardiac left ventricular function, as assessed by CMR, in subjects with differentiated thyroid cancer during their early treatment.Secondary Objective(s): To compare…
To investigate whether circadian rhythms in patients with chronic systolic heart failure are disturbed
The primary objective is to demonstrate that rivaroxaban is superior to placebo in subjects with chronic HF and significant CAD, who are receiving standard care, in reducing the risk of the composite of ACM, MI, or stroke following a recent…
1) To study the late effects of 131-I treatment and TSH suppressive therapy as well as quality of life in patients with childhood-onset DTC. 2) To determine the presence of RET/PTC 1 and 3 translocations and BRAF mutations, and to investigate their…
The aim of this study is to evaluate the effects of treatment on the exertional contractile reserve and RV-arterial coupling during exercise in CTEPH patients. Furthermore, we evaluate the effects on the exertional contractile reserve and RV-…
The primary objective of this study is to identify in which imaging modality, including CE and vortex imaging, could help us in the early diagnoses of intracardiac thrombosis in LVAD patients. We attempt to provide a more dedicated method for the…
Primary Objectives: - To investigate whether disease progression in individual patients with CHF can be accurately assessed by serial measurements of disease-related (novel) biomarkers.- To investigate whether dynamic biomarker patterns as…
Primary Objective: -To test the feasibility of MRI and CT fusion with 3D rotational venogram / fluoroscopy for left ventricular lead positioning in CRT.Secondary Objectives: -Visualize the location and distance to LV lead position of MRI determined…
Is to identify the incidence and prevalende of PH in premature born infants. In addition we will identify possible risk factors for the development of PH and we want to determine the prognosis and survival of these patients. PrimaryTo determine the…
Hypothesis - Our hypothesis is that TNF blocking medication improves cardiac function in patients with active RA. Objectives - Primary objective: to investigate the effect of TNF blocking therapy on diastolic left ventricular (LV) function in RA…
Concordance between MET diagnosis with and without the use of ultrasound with the chart review definitive diagnosis will be studied. Also other secondary endpoints will be evaluated.
To determine the tacrolimus bioavailability after tacrolimus administration via a rectiole.
Measuring cardiac output using TTE with and without the use of ProbeFix in adult Intensive Care patients in which a PLR test is used as a fluid challenge. The possible changes in cardiac output measured with TTE are compared with the measurements…
The primary objective is to correlate the properties of the right ventricular strain-area loop to the properties of the right ventricular pressure-volume curve.
To establish a healthy control group for microcirculatory parameters for current and future studies on the paediatric microcirculation.
The purpose of the study is to investigate how quickly and to what extent neladenoson bialanate is absorbed, distributed, metabolized (broken down) and eliminated from the body (this is called pharmacokinetics). Neladenoson bialanate to be…
To study patients with severe HF who would benefit from off-pump SVR using the Revivent Myocardial Anchoring System. To investigate the characteristics of the ischaemic heart using CMR or cardiac CT in order to verify patient eligibility for the…
The primary objective of the study is to determine whether the intrinsic electrical delay (QLVs) at a specific pacing site is correlated to acute hemodynamic response (by percentage increase in strokework, %SW) in CRT with a quadripolar lead.
Primary Objective:To demonstrate that serelaxin is superior to placebo in reducing CV death in AHF patients during a follow-up period of 180 days.To demonstrate that serelaxin is superior to placebo in reducing worsening heart failure through Day…
The purpose of the MultiSENSE study is to collect chronic ambulatory data simultaneously from multiple sensors in CRT-D devices in order to develop algorithms for the early detection of worsening HF. The primary objectives of this study are to…