21 results
To assess and compare long term scar quality of deep dermal burns after debridement with hydrosurgical- and conventional tangential excision.
To determine long-term scar quality in patients admitted to a Dutch burn centre with burn wound of indeterminate depth.
To obtain a comprehensive overview of long-term (*5 years after burn injury) consequences after burn injuries, both in all patients admitted to burn centre admissions and in a subgroup of patients who suffered from more extensive burns.
The goal of this study is to develope and validate a non-invasive method for the age determination of bruises. This method is tested on adult volunteers. We expect differences between the healing proces of bruises in adults and children.To be more…
The Activation of Coagulation and Inflammation in Trauma (ACIT) study is designed to identify the clinically significant mechanisms and pathways by which inflammation and coagulation are activated immediately following major trauma, and how these…
In this study we want to investigate if there are differences in cytokine and mFABp production when using a rigid and a soft-layered spineboard, in relation to tissue-interface pressures. Furthermore, redness of the skin and experienced comfort are…
The primary objective of this study is to evaluate if there are differences in the tissue-interface pressures, pressures inside the tissues and tissue deformation in the sacral area when volunteers lie on a regular spineboard versus a vacuum…
Primary objective: to investigate the possible role of FABP/Claudin levels as a diagnostic marker for significant intra-abdominal injury (necessitating therapeutical intervention).Secondary objective: to establish the use of plasma levels of I-FABP/…
The main objective of this multicentre interdisciplinary study is to systematically aggregate data on moderate and severe traumatic brain injury patients in a national database. This database will serve to:a. get an estimation of the incidence of…
Aim of this study is to investigate the level of functioning and the quality of life of children and young adults, six to eight years after major trauma.
The primary objective of this project is to demonstrate the equivalence of treatment of traumatic splenic injury with splenic artery embolization (SAE) compared to splenectomy and non-operative management (NOM) in terms of quality of life measured…
To determine the accuracy and robustness of this method it is necessary to validate it. In the past some successful studies have been performed in adult volunteerd. However we would like to investigate the influence of induced changes to the healing…
To determine the accuracy and robustness of this method it is necessary to validate it. In the past some successful studies have been performed in adult volunteerd. However we would like to validate the model based on bruises that where induced with…
The Activation of Coagulation and Inflammation in Trauma (ACIT) study is designed to identify the clinically significant mechanisms and pathways by which inflammation and coagulation are activated immediately following major trauma, and how these…
Research into the influence of cooling on bruise development measured using reflection spectroscopy.
To determine the accuracy and robustness of this method it is necessary to validate it. In the past some successful studies have been performed in adult volunteerd. However we would like to investigate the influence of induced changes to the healing…
Primary Objective: to determine the pathophysiology of post-extubation dysphagia in ICU patients after prolonged endotracheal intubation using simultaneously recorded flexible endoscopic evaluation of swallowing (FEES), high resolution impedance…
This study has been transitioned to CTIS with ID 2024-514488-24-01 check the CTIS register for the current data. Primary Objective: To determine the safety and efficacy of 6000 IU Cinryze in patients with moderate and severe TBI (GCS <13 with…
Primary objective:i. Investigate cerebrospinal fluid (CSF) polyol concentrations in patients following traumatic brain injurySecondary objectives:i. Investigate the association between plasma glucose, CSF glucose and CSF polyols following traumatic…
Primary Objective: To investigate the effect on the distention of the ONSD while using lidocaine 1,5 mg/kg IV during endotracheal intubation versus placebo. Secondary Objectives: The secondary objective of this study is to investigate the effect…
The primary objective of this project is to demonstrate the equivalence of treatment of traumatic splenic injury with splenic artery embolization (SAE) compared to splenectomy and non-operative management (NOM) in terms of quality of life at…