30 results
The main objectives of this study are to evaluate the safety and performance of the AutoLap system in the following laparoscopic procedures: hernia repair, cholecystectomy, right colectomy, Nissen fundoplication and sigmoidresection. The AutoLap…
To assess whether a combination of ciprofloxacin and adalimumab is more effective than adalimumab alone.
To determine the efficacy, safety and patient tolerability of spiral endoscopy for use in colonoscopy.
The aim of this study is to find a succesful treatment for chronic abdominal pain and small intestinal bacterial overgrowth in children and at the same time improve the quality of life of these children. A second aim is to reduce the hospital visits…
To test whether probiotics, as adjuvant therapy, can reduce incidence and severity of migraine attacks by reducing intestinal permeability.
Primary objective: To explore whether prolonged moderate alcohol consumption affects in vivo cytokine response after a low dose of LPS in young, normal-weight men.Secondary objectives: To explore whether prolonged moderate alcohol consumption-…
The aim of the present study is to validate this model in a Dutch CD patient population.
To obtain insights into the diverse nuclear receptors involved in the regulation of the bile acid cycle across the entire human gastrointestinal tract. Amendement:The aim of our study is to investigate the expression and amount of expression of HIF-…
Effectiveness of treatment with clioquinol on parasitologic eradication is being studied as well as the clinical effectiveness of eradication in children with dientamoeba fragilis infection.
To determine the efficacy and tolerability of L-Autogel in patients with early or late dumping syndrome after gastric surgery.
Primary objectivel: assessment of liver fibrose in children with cystic fibrosis, using transient elastography (Fibroscan). Results will be compared with other surrogate markers of CFRLD: liver ultrasonography and biochemical markers: AST, ALT, PT,…
Primary objective: assessment of liver fibrose in children with cystic fibrosis, using transient elastography (Fibroscan). Results will be compared with other surrogate markers of CFRLD: liver ultrasonography and biochemical markers: AST, ALT, PT,…
Comparison of three cleansing solutions for bowel preparation prior to colonoscopy.
Determine the gastric and neural correlates of bloating.
To evaluate the performance of MCS in cleansing a poorly prepared colon.
Study the frequency and severity of hyponatremia caused by Picoprep bowel preparation.
Objective: to determine the feasibility of planned eating and drinking in preparation for oeshophagus-gastroduodenoscopy.
Aim: To investigate the efficacy of nortriptyline in FD patients with a predicted CYP2D6 extensive metabolizer phenotype. Nortriptyline is a second generation TCA with significantly fewer anticholinergic side effects compared to the first generation…
We aim to perform a proof-of-concept study to assess the effect of ATIs on the intestinal barrier and immune function in healthy volunteers. We hypothesise that the ATIs either directly affect the intestinal barrier function, or indirectly by…
Primary objective is to elucidate the natural course of pain after abdominal surgery. Secondary objectives are assessment of risk factors for development of chronic pain after surgery, and comparison of adhesion formation between patient with and…