16 results
This study aims at (further) revealing the pathophysiology of intestinal IR in man, with a specific interest for the role of proteases and protease-activated receptor-2 (PAR-2), cellular and inflammatory changes, barrier function and intestinal…
We will investigate the effect of the combination of moderate physical activity and a standard meal on the onset of low grade intestinal ischemia. Will will use the serological biomarker I-FABP to determine the occurrence of low grade intestinal…
* To determine the minimum effective dose of 5-aminolevulinic acid (Gliolan) for adequate MitoPO2 measurements during upper endoscopy.
Primary Objective: for each new catheter design: in-vitro establishment of time-dependent correction factors for saline-use and establish the accuracy of CO2 measurement with the capnograph. In-vivo: establish the feasibility and measurement errors…
- Primary Objective: to investigate whether the administration of a small amount of dobutamine postoperatively is able to positively influence the sublingual microcirculation in patients who are undergoing esophagectomy.- Secondary Objective: to…
To evaluate the prevalence of gastrointestinal ischemia in patients with acute and chronic non-cirrhotic, non-malignant PVT.
First goal is the evaluation of plasma and urinary FABP levels as useful indicators for diagnosis of intestinal ischemia. Second goal is to study whether combinations of proteins from the family of FABPs provide insight in the localization of…
To assess the benefits and harms of SUP with PPI in adult, critically ill patients in the ICU.
To determine the feasibility of the MitoPO2 measurements during upper endoscopy.
This study aims to investigate whether the intraoperative use of indocyanine green fluorescence angiography (ICG-FA) is feasible and safe in neonates. Feasibility is therein defined as practically possible use of ICG-FA, resulting in clear and…
The goal of this study is to investigate the most optimal way of canola protein processing on blood plasma amino acid responses in young females.
To determine the difference in baseline MR flow measurements and post-prandial MR flow measurements between patients diagnosed with CGI and patients not diagnosed with CGI. To gather information on the potential of endoscopic mitochondrial oxygen…
Facilitating diagnosis of chronic mesenteric ischemia (CMI) using 1) the mesenteric artery calcium score (MACS) and 2) mucosal ischemia detection by butyrate breath testing
To assess procedural hemodynamic indices of paravalvular leakage and to relate these to cardiac MRI at 1 month and clinical follow-up over 5 years.To diagnose angiodysplasia en determine the effect of TAVI on these angiodysplastic lesions.
Intra-arterial pressure measurements are currently the most promising tool to guide clinical decision making in patients with suspected CMI. Implementation of pressure measurements could result in major improvements in quality of life by tailoring…
Primary objectives: - to determine the inter-observer variability of VLS- to determine the intra-observer variability of VLSSecondary objectives:- to determine the inter-observer variability of VLS per specific measurement location: antrum of the…