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Preventing severe infection after splenectomy

The aim of this study is to evaluate the current practice of anti-infectious strategies in patients with an absent or dysfunctional spleen.

Effectiveness and cost-effectiveness of lymphaticovenous anastomosis for cancer patients who suffer from chronic peripheral lymphedema

Primary Objective:The primary objective is to assess the efficacy of LVA surgery in comparison to sham procedure in patients with cancer related lymphedema in the context of improvement of Lymph-ICF score at 12 and 24 months follow up. Secondary…

Lymphomics; improving the understanding of the anatomy of the lymphatic system and the direction and velocity of lymph flow

To improve the knowledge and understanding of the (patho)physiology of lymph disorders Main objective: the anatomy of the central lymph vessels, the velocity and direction of lymph flow and its influencers and thoracic duct outlet location and…

Improving the understanding of the anatomy and lymph flow in the central lymphatic system in patients with Noonan Syndrome Spectrum Disorder

To get a better insight into the central conducting lymphatic system in adult volunteers with Noonan Syndrome (NS) without clinical symptoms or signs of lymphatic disease compared to NS and CardioFacioCutaan syndrome patients with severe lymphatic…

Medical assessment of adverse health outcomes in Dutch childhood cancer survivors; a nationwide project; SKION LATER Q2008 onderzoek:
Impaired splenic function in long-term survivors of childhood cancer; diagnostic and therapeutic strategies.

Primary aims:1. To assess the efficacy of pneumococcal vaccination in patients with impaired splenic function after cancer therapy. 2. To compare the number of IgM memory B-cells of survivors after splenectomy with survivors who received TBI, and…