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Clonidine: een veelbelovende toevoeging aan de huidige behandeling van schizofrenie.

-Six weeks of treatment with a supplementary low dose of clonidine to the current medical treatment of clozapine resistant patients will effectively reduce symptom severity and cognitive impairments in therapy resistant schizophrenia patients -…

Use of monomeric and oligomeric flavanols in the dietary management of patients with type 2 diabetes and microalbuminuria

We hypothesize that monomeric and oligomeric flavanols (MOF) have a beneficial effect on renal-endothelial function in the dietary management of T2D, as reflected by improvement of AER and renal-endothelial biomarkers.

The Effect of Vitamin D on the Consolidation of Extra-articular Fractures - a double-blind randomized controlled trial

Vitamin D supplementation reduces the incidence of delayed union in fracture patients with a vitamin D insufficiency, compared to placebo.

A smoking cessation intervention: online cognitive bias training

1. Participants in the CBM training condition have weaker smoking related cognitive biases than those in the placebo condition 2. Improvement in smoking cessation outcomes in participants in the CBM training condition compared to those in the…

Effectiveness of radiotherapy in osteoarthritis of the hand and knee

-Low dose radiotherapy has positive effects on pain and functioning in osteoarthritis of the hand and knee -Low dose radiotherapy is effective on reducing inflammatory signs of osteoarthritis of the hand and knee

Study on the effects of a growing-up milk (GUM)on infections in healthy children

Consumption of the new developed GUM will decrease the incidence of upper respiratory tract infections (URTI) and/or decrease the duration of acute gastrointestinal tract infections (GITI) in Asian toddlers

Treat early arthralgia to reverse or limit impending exacerbation to rheumatoid arthritis

This proof-of-concept study aims to determine whether intervention in the preclinical phase in symptomatic patients at risk for RA is effective in progression from subclinical inflammation to clinically apparent persistent arthritis.

Effect of perioperative ketamine on postoperative cognition – a randomized placebo-controlled trial

We hypothesize that perioperative ketamine will reduce cognitive decline in postoperative patients, in line with its analgesic and anti-inflammatory properties.

A trial to determine the efficacy of dry powder mannitol in improving lung function in subjects with Cystic Fibrosis aged six to seventeen years

It is hypothesised that inhaled mannitol 400 mg b.d. will lead to a significant improvement in the absolute change in percentage of predicted FEV1 from baseline following eight-weeks of trial treatment compared to treatment with inhaled placebo b.d…

Hypertonic saline in Primary Ciliary Dyskinesia: a pilot study

We hypothesize that bi-daily 5ml NaCl 7% nebulizations improve respiratory symptoms and quality of life in PCD patients compared to 5ml NaCl 0,9% nebulizations.

Protein and lifestyle intervention to preserve muscle mass in obese older type 2 diabetes patients – a 13-week randomised, controlled exploratory study with a 24-week follow-up period.

H0: The effect of using test intervention is equal to the effect of the control intervention with respect to change in leg muscle mass in obese older adult patients with type 2 Diabetes after 13 weeks of intervention H1: The effect of using test…