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The development of a thirst provocation test using the AVP receptor antagonist Tolvaptan for quantification of thirst sensation in various patient groups (obese patients with and without a history of bariatric surgery, patients with congestive heart failure and patients with cranial diabetes insipidus as compared to healthy controls) and genotyping of the AVP receptor 2.

We aim to investigate thirst in the above mentioned patient groups, applying a Visual Analogue Scale (VAS) and, where ethically acceptable, a new thirst provocation test which we will develop in a group of healthy probands. Using these tools, we aim…

Perioperative esmolol infusion for haemodynamic stability during major vascular surgery.

Primary Objective: comparing hemodynamic stability provided by titration of esmolol in addition to standard perioperative care including low-dose metoprolol to placebo and standard care.Secondary Objective(s): -comparing the incidence of…

Interventions with Music in Pectus Excavatum Treatment

This research will investigate a non-pharmacological, low-cost, durable and safe method during and after pectus excavatum surgery, to alleviate postoperative pain and thereby reduce the dose of analgesics used. Our secondary aim is to investigate…

Exploring the early healing potential of a novel thermosensitive hyaluronic acid gel with octenidine preservation system as an adjunct to non-surgical periodontal treatment: a split-mouth blinded pilot study with proteomic analysis

This pilot study aims to assess the feasibility, safety and preliminary efficacy of a novel thermosensitive hyaluronic acid gel with an octenidine preservative system as an adjunct to standard non-surgical periodontal treatment. The use of a blinded…