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The analgesic efficacy of Δ9-THC (Namisol®) in patients with persistent postsurgical abdominal pain: a randomized, double-blinded, placebo-controlled, parallel design

Primary Objective: - To investigate the analgesic efficacy of a stable dose Namisol® in patients suffering from persistent postsurgical abdominal pain. Secondary Objectives:- To investigate the effect of a stable dose Namisol® on central nervous…

Does Misoprostol facilitate insertion of an Intra Uterine Device (IUD), both copper-containing as well as levonorgestrel-releasing, among nulli- and multipara?

To investigate whether Misoprostol (compared to placebo) will diminish the amount of insertion failures. To investigate whether Misoprostol (compared to placebo) will diminish the amount of insertion related complications (eg. syncope, perforation…

OTR4120: topical application to split-skin graft donor sites. A clinical evaluation on the healing.

Objective: To demonstrate the efficacy of a novel matrix therapy based technology that creates improved wound healing in a clinical donor site model.

Driving under the influence of Drugs, Alcohol and Medicines
Effects of dexamphetamine with and without alcohol on simulated driving

To assess the effects of dexamphetamine with and without alcohol on simulated driving performance.

Complement Inhibition: Attacking the Overshooting Inflammation @fter Traumatic Brain Injury ( A phase II trial on the safety and efficacy of C1 esterase inhibitor Cinryze for the acute management of severe traumatic brain injury)

This study has been transitioned to CTIS with ID 2024-514488-24-01 check the CTIS register for the current data. Primary Objective: To determine the safety and efficacy of 6000 IU Cinryze in patients with moderate and severe TBI (GCS <13 with…

The effect of intravenous lidocaine to prevent intracranial pressure increase in endotracheal intubation assessed by optic nerve sheath diameter

Primary Objective: To investigate the effect on the distention of the ONSD while using lidocaine 1,5 mg/kg IV during endotracheal intubation versus placebo. Secondary Objectives: The secondary objective of this study is to investigate the effect…

MORphine use in the Fascia Iliaca Compartment block with UltraSound

The main study endpoint will be the mean preoperative morphine use per hour in patients with and without FICB with levobupivacaine, guided by ultrasound. Secondary parameters will include the pain scores reported by the numerical rating scale both…

CE marking for the Q-whet micro current wound stimulator

Objective:The objective of the study is to test the hypothesis that the QWHET micro current wound stimulation device has minimal side effects. The study will be designed as a double blind, prospective study.The results will be used to obtain a CE…

Femoral Nerve Blockage in Proximal Femoral Fractures in patients of 65 years of age or older, a Randomised Controlled Trial

The objective of this study is to determine the clinical outcomes of ultrasound guided femoral nerve blockage using intermitting shots of levobupivacaine, in patients with hip fractures and to compare these results with placebo injections.The…