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A randomized, controlled, single-blinded, multicenter clinical trial to evaluate the percutaneous radiofrequency treatment of facet joint pain versus a sham-operated group

Investigate the value of percutaneous radiofrequency heat lesion, applied to the medial branch of the primary dorsal ramus; more specifically try to determine if a significant and long lasting pain reduction can be obtained as compared to a sham-…

Local Infiltration Anaesthesia in Total Hip Arthroplasty by Anterior Supine Intermuscular Approach

Determining the outcome of reversed and antegrade LIA in THA with ASI by analysing postoperative pain with the 100 mm Visual Analogue Scale (NRS), length of hospital stay, the amount of postoperative consumption of opioid pain medication as well as…

A randomized, single-blind, placebo controlled, parallel-group study evaluating the anti-inflamatory activity of GSK315234 in synovial biopsy tissue obtained from subjects with rheumatoid arthritis (OSM105196)

Primary ObjectivesTo assess the change in inflammatory biomarkers in the synovial tissue of subjects with RA on a background of methotrexate after administration of a single, intravenous dose of GSK315234, as compared to placebo. To assess the…

The efficacy of the IDD-protocol with Accu-Spina for patients with low back pain

The primary objective of the study is to investigate whether the IDD (Intervertebral Differential Dynamics) protocol with Accu-Spina on the VAS low back pain score at 3 months posttreatment.

The influence of musculoskeletal physiotherapy on the immune response in patients with neck pain.

The overall aim of this study is to gain insight into the pathophysiological mechanism of patients with non- specific neck pain and cervical radiculopathy and the influence of MP on these mechanisms. Therefore, different research objectives are…