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Optimizing the amount of dietary protein to maximally stimulate post-exercise muscle protein synthesis in elderly men.

To define the amount of dietary protein required to optimally stimulate post-exercise muscle protein synthesis in the older population.To assess whether co-ingesting 1.5 g of free leucine (contained within 15 g dairy protein) along with 15 g protein…

The effect of Neuromuscular Electrical Stimulation on post-prandial muscle protein accretion in healthy elderly men

The aim of this study is to investigate the effect of a single bout of NMES on muscle protein synthesis rates in healthy elderly males.

Protein feeding prior to sleep as a dietary strategy to improve post-exercise recovery and muscle mass in young and elderly men

The primary objective of this study is to investigate the effect of a meal-like amount of dietary protein prior to sleep on postprandial muscle protein synthesis in healthy young and elderly men, following exercise, during the night. Furthermore, as…

The manipulation of dietary protein intake on the anabolic response in healthy young men

STUDY 1: To investigate the impact of prior ingestion of a single high protein meal on the normal obligatory increase of muscle protein synthesis rates after protein intake and physical activity in healthy young men. STUDY 2: To investigate the…

The effects of protein type and added leucine on post-exercise muscle protein synthesis

Overall Objective: To define the properties of whey, casein, milk protein, as well as soy protein with and without additional leucine to augment post-exercise muscle protein synthesis when co-ingested with a carbohydrate containing recovery drink.…

The effects of protein dose response on myofibrillar and mitochondrial protein synthesis after endurance exercise in young men.

To define a dose-response relationship after intrinsically labeled milk protein ingestion on myofibrillar and mitochondrial muscle protein synthesis after a single bout of endurance exercise.

The effect of a single session of whole-body neuromuscular electrical stimulation (NMES), with or without subsequent intake of a protein bolus, on whole-body protein turnover in sedated intensive care unit (ICU) patients

To examine the effect of a single session of whole-body NMES, with or without subsequent protein intake, on whole-body protein turnover

The effect of collagen supplementation on collagen metabolism after total hip arthroplasty.

We aim to determine the effects of collagen supplementation on biomarkers of collagen metabolism in the two weeks following total hip arthroplasty in older adults with osteoarthritis.

A phase 3 study of PTC923 in subjects with phenylketonuria

Primary:• To evaluate the efficacy of PTC923 in reducing blood phenylalanine (Phe) levels in subjects with phenylketonuria (PKU) as measured by mean change in blood Phe levels from baseline to Weeks 5 and 6 (ie, the average of each respective…

The effect of repeated sessions of whole-body neuromuscular electrical stimulation (NMES), with or without subsequent intake of a protein bolus, on muscle protein synthesis in healthy, young volunteers during 3 days of bed rest.

To investigate the effect of multiple sessions of whole body NMES, with or without consecutive protein intake, on muscle protein synthesis.

REDUCING EARLY ATROPHY WITH LEUCINE DURING IMMOBILIZATION OF SKELETAL MUSCLE

Primary Objectives:1. Determine the impact of short-term (3 days) unilateral lower-limb immobilization on *cumulative* rates of MPS in younger and older adults.2. Determine whether leucine supplementation can prevent declines in cumulative MPS and…