9 results
Primary:To estimate the treatment effects of vildagliptin 50 mg PO BID on 24h weighted-mean glucose (WMG), using CGM and plasma glucose, collected at the end of a two-week treatment period.Secondary:1) To estimate the treatment effects of…
Primary Objective: The primary objective is to determine whether the administration of Gelofusine will reduce the kidney uptake of 111In-labeled exendin in humans by enhancing the excretion of 111In-labeled exendin. These highly relevant data can…
We hypothesize, that during an oral glucose tolerance test, the OPS arterial flow measured sublingual will be comparable within the same subject, but different between young, elderly and type 2 diabetic patients. Objective is to quantify differences…
to measure peripheral insulin sensitivity and intramyocellular concentrations of different FA metabolites (ceramide, gangliosides, diacylglycerol and triacylglycerol) known to interfere with the insulin signalling cascade during infusion of…
We aim to study the short-term effects of postprandial hyperglycemia in patients with impaired fasting glucose and in patients with T2DM on aortic stiffness as measured by PWV. Secondly, we study the effects of postprandial hyperglycemia on the…
Part I: The objective of Part I of this study is the efficacy of a single 5-g and 10-g dose of InsuVital* on blood levels of insulin and glucose in patients with T2DM.Part II: The objective of Part II of this study is to assess the effect of a 10-g…
Objective: To explore whether 1) acute sensory stimulation in the oral cavity by means of alcoholic beverage (=white wine) induces a cephalic phase reflex (CPR)2) prolonged moderate alcohol consumption affects gene expression pathways of…
To examine the effect of a single session of whole-body NMES, with or without subsequent protein intake, on whole-body protein turnover
The main objective of this study is to look at the effect of iv acetate infusion on postprandial glucose metabolism and whether this effect differs between healthy lean subjects and obese subjects with metabolic syndrome.The secondary objectives of…