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Positional therapy in patients with positional Obstructive Sleep Apnea Syndrome: A randomized controlled trial

Primary objective: To assess the efficacy of reducing the sleep time in supine posture with positional therapy using the position training device compared to the sleep position band in patients with mild and moderate positional OSAS.Secondary…

EVALUATION OF THE EFFICACY AND SAFETY OF 6 REPEATED DAILY
DOSES OF NEBULISED RPL554 0.018 mg/kg (6X)
IN ALLERGIC ASTHMATICS

To investigate the efficacy of repeated daily doses of nebulised RPL554 (0.018 mg/kg) by assessing the effect on FEV1 at day 1, 3 and 6 after daily inhaled doses of nebulised RPL554 0.018 mg/kg (6X) in 16 allergic asthmatics.

Evaluation of the effect of the AlphaCore* on breathlessness and time to discharge in hospitalised subjects with COPD

The AlphaCore* is currently being used in some hospitalised COPD subjects, as adjunctive treatment to regular care. This use is conform CE and is showing diminished breathlessness in some subjects. For further investigation of these results, this…

The effect of inhaled heparin on pulmonary coagulation activation and vascular permeability in mechanically ventilated patients with acute lung injury / acute respiratory disress syndrome

Objectives1. to determine whether nebulization of heparin decreases coagulation activation in the pulmonary compartment (i.e. BAL fluid)2. to determine whether nebulization of heparin decreases pulmonary vascular permeability