183 results
The study will assess drug-induced change in performance in divergent thinking and goal-directed behaviour when comparing psilocybin to placebo, before and after an induction of stress. Additional study parameters include frontal-subcortical…
Based on previous studies, we will expect that ambroxol improves neurological manifestations in patients with GD3.
To evaluate whether a dietary advice of green vegetables, beef and whole dairy products during six months including standard supportive care can decrease the TSH-level compared to standard supportive care alone in children aged 1-18 years with…
The administration of propranolol will inhibit the increase in dermal blood flow (DBF) induced by capsaicin application.
We hypothesize that in healthy individuals with Early-life stress (ELS), THC, which directly targets the endocannabinoid system, is more effective than hydrocortisone in improving stress adaptation and extinction learning in an experimental model of…
Electroconvulsive therapy (ECT) is the most effective treatment for severe depressions. Unfortunately, several cognitive side effects with a large pallet of different manifestations and impact often occur. For instance, postictal agitation ((PIA)…
We hypothesize that iABM patients, relative to controls, will show less addiction problems, increased health, reduced physical and psychological complaints, and reduced use of health care post-intervention and at 6 & 12 month FU Further, we…
Inhibition of the H1 receptor will lead to an improvement of rectal sensitivity, followed by less abdominal symptoms in patients with irritable bowel syndrome.
We expect better outcomes: ABC > CBM > sham-CBM
Adding Paracetamol to treatment with Remifentanil/ Patient Controlled Analgesia for management of labour pain ("multimodal pain management") reduces opioid (Remifentanil) consumption
1. We hypothesize that the ingestion of 30 g of collagen peptides and 30 g of free amino acids (matching the profile of collagen peptides) will result in greater myofibrillar and connective tissue protein synthesis rates in skeletal muscle tissue at…
1. Addition of weekly pegvisomant administrations improves quality of life; 2. Addition of weekly pegvisomant administrations improves insulin sensitivity.
SCH 351125 50 mg BID 2/days is an effective treatment for RA.
We will investigate the relationship between S(+)-ketamine plasmaconcentrations and its analgesic effect to estimates the onset/offset times of ketamine and potency parameters for various analgesia tests. This will allow the safer administration of…
We hypothesized that adding alimemazine to existing ADHD treatment will decrease ADHD-symptoms as reported by parents and school teachers as well as allergic symptoms.
1. After completing real approach bias re-training, participants will show a stronger reduction in approach bias for alcohol than after placebo training (main effect 1); 2. After completing real attentional bias re-training, participants will show a…
Primary Objective: Investigate the effect of modafinil (200 mg) and caffeine (300 mg) on vigilance in low, medium and high caffeine consumers during the circadian trough in order to determine: - To what extend vigilance during the circadian trough…
The present mode of (tonic) SCS is accompanied by paraesthesia in the area of stimulation. Recently, a new mode of SCS has been developed which makes it possible to apply spinal cord stimulation without paraesthesias. This mode is called burst…
Prevention of respiratory syncytial virus infection using palivizumab in preterm children with gestational age 32-35 weeks will result in decreased incidence of recurrent episodes of wheeze (post-bronchiolitis wheeze).
Extension of SAD PK/PD Model, confirmation of SAD PD effects