15 results
Primary Objective- To demonstrate dose proportionality between 1 mg and 5 mg of PedPRM (Neurim Pharmaceuticals Ltd.) following a single oral dose in healthy male and female volunteers (treatment A and C), under fed conditions.Secondary Objectives-…
Primary Objective: To determine the effectiveness of guided CBT compared to care-as-usual in treating insomnia in the general practice.Secondary Objective(s): Secondary objectives include investigation of cost-effectiveness. Several variables will…
The present study aims to systematically investigate whether the thermoregulatory profile of spontaneous fluctuations and responses to perturbations differs in association with diagnosis and with individual differences in the severity of vigilance…
The objective of this study is to determine whether providing feedback enhances self-help CBT for insomnia.
The objective of this study is to validate a newly designed self-help treatment for nightmares. This self-help treatment is based on Imagery Rehearsal Therapy. This treatment will be validated in comparison to an exposure treatment a diary condition…
As part of the development of the guided web-based self-help intervention for insomnia we want to conduct a pilot study. The aim is twofold: (1)we want to know how satisfied people are with this course. Specific questions are: what are the…
The major aim of the proposed project is to investigate the clinical relevance of early identification and adequate treatment of co-occurring sleep disorders in people suffering from mental disorders. The main questions underlying the present…
Objectives: 1) to evaluate the effectiveness of the e-CBT-i *i-Sleep* compared to a waiting list condition on sleep efficiency at 3, 6 and 12 months in ACC. 2) to assess the effects of eCBT-I on secondary outcomes: fatigue, quality of life, chronic…
To investigate the effect of sleep treatment on ADHD, mood and sleep quality.
1. Provide evidence for the clinical effectiveness of dCBT-I for the treatment of insomnia symptoms in pregnant woman with psychiatric vulnerability. 2. Provide evidence for the effectiveness of insomnia treatment and the positive effects on mental…
The current study aims to investigate two types of sleep interventions in night shift workers: a split sleep intervention strategy and a short sleep episode (powernap, max. 20 min) during a night shift. It will assess the effects of the two…
The current project aims to assess both the effectiveness and cost-effectiveness of an internet-based insomnia intervention (i-Sleep) in addition to usual care for depression, compared to usual care alone, in depressive patients with comorbid…
We hypothesize that improving sleep will improve glycaemic control in people with T2DM and insomnia. To test this hypothesis, we established the following objectives: 1) investigate if improving sleep by internet-based cognitive behavioural therapy…
This is the first study to create and investigate the effectiveness of a multi-component intervention protocol in students with sleep problems. The aim is that such an intervention, combining cognitive-behavioural therapy for insomnia, mindfulness,…
The main objective of this study is to evaluate the efficacy of an eHealth cognitive behavioural intervention to treat insomnia in people with acquired brain injury.