150 results
The aim of this study is to investigate the effectiveness of EMDR with traumatized adolescents (12-18 years) with major depressive disorder.
Aim of this study is to examine the mechanisms by which attachment style and emotion regulation relate to depressive symptoms and anxiety symptoms in a clinical and non-clinical Dutch population.
Main: 1. To investigate whether a short term CBT-based group program is more effective in reducing symptoms of depression and anxiety than treatment as usual (TAU), among adolescents aged 10-16 within residential treatment settings in the youth…
The primary objectives are (1) to investigate the feasibility of online courses targeting nutrition and food-related behaviour and (2) to investigate whether the feasibility of the online courses is related to depressive symptoms. The secondary…
Objective: We would like to differentiate *normative mood swings*. in adolescence from early signs of depression. A comparison between low-risk adolescents and an at risk and a clinically referred sample is needed to detect an unrecognized subsample…
The effectiveness of psychotherapy can be improved by increasing the frequency of sessions at the beginning of therapy. In addition, understanding processes that account for therapeutic change might enable us to optimize treatments.
The primary goal is to evaluate the effectiveness of a screening and prevention program for adolescents who experience depressive symptoms. The secondary goal is to find factors which possibly relate to the effectiveness of the prevention program.…
Compare the clinical- and cost-effectiveness of blended cognitive behavioral treatment (bCBT) to treatment as usual (TAU) for adults with MDD in specialised ambulatory mental healthcare.
This study aims at the questions about anterograde amnesia. How often does it occur in patients being treated with bilateral ECT for a depressive disorder, how does anterograde amnesia develop during the treatment course and how does it subside…
This study investigates if the BeweegKuur Depressive Symptoms is more (cost-)effective in comparison with "watchful waiting". Complementary, success factors and barriers of the implementation of the BeweegKuur Depressive Symptoms in…
Primary Objective: * To determine the effects of pharmacogenetic screening for CYP2D6 on the time to reach adequate serum drug levels according to the guidelines.Secondary Objective(s): * To determine the effects of pharmacogenetic screening for…
Overall, our primary research goal is to elucidate the underlying molecular and cellular neurobiology of depression. Specifically, this study will focus on the following key objectives:1. My first objective is centered on the major prevailing…
This study aims to investigate the neurobiological basis underlying the strong antidepressant effect of ECT in patients with unipolar and bipolar depression using MRI. We will also assess a potential neurobiological basis for the cognitive side-…
Can this effect be utilised clinically, especially in patients with major depressive disorder?
We will examine effectiveness of the internet-based self-help intervention compared to a waiting list control condition on (1) reduction of depressive and anxiety symptoms post intervention and 6 weeks post-partum and (2) improvement in perinatal…
To evaluate the cost-effectiveness of a nurse-led stepped-care program for depression among primary care patients with type 2 diabetes mellitus and/or coronary heart disease and subtresshold depression in comparison with usual care.
The objective of this study is threefold:1) compare the effectiveness and cost-effectiveness of brief CT added to maintenance AD versus maintenance AD alone versus guided tapering or discontinuation of AD with brief CT.2) examine whether the…
Aim of the study is to evaluate the effectiveness and cost-effectiveness of a positivity training based on attention bias modification as waitlist-intervention for adult outpatients with a major depressive disorder.
This pilot cost-effectiveness study will compare blended cognitive behavioral treatment (bCBT) with standard face-to-face CBT (CBTAU) among patients with a diagnosis of major depressive disorder (MDD), who are treated in outpatient specialized…
Objective: Primary objective is to demonstrate non-inferiority of the e-prescription to the use of antidepressants on the short term. Secondary objectives are to assess its effect on long term outcomes, antidepressant use, and to assess its…