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HOMERUN
Initiation of HOme MEchanical ventilation at home in a selective group of patients with chronic hypercapnic Respiratory failUre in the Netherlands

Patients with chronic respiratory failure currently start their ventilatory support in hospital as stated in national guideline. However, as these patients are severely disabled, a stay at the hospital for several days is experienced by many as very…

Control of breathing in systemic sclerosis

-To assess the central chemosensitivity by an carbon dioxide rebreathing test-To assess mouth occlusion pressures during the carbon dioxide rebreathing test-To study the relation between these results and the results obtained with the MRI and…

Initiation of chronic ventilatory support outside the hospital.

We want to investigate if it is possible to set up the entire process of home mechanical ventilation outside the hospital. This means practically that the patients will not be admitted to the hospital. The goal of this study is to answer the…

Vacuum-Assisted Closure versus Closed Drainage using Redon Catheters for the Treatment of Mediastinitis: a Prospective Study

.Currently, vacuum-assisted drainage and closed drainage using redon catheters are widely accepted methods for the treatment of mediastinitis. However, it is unknown which technique is considered to be the most effective. We hypothesize that closed…

The Cardio Thoracic Harness

The objective of this study is to get insight in the effect of the Cardio Thoracic Harness for men and the Cardio thoracic bra for women. The harness and the bra possibly have an important role in pain management. The producer of the harness and the…

Effects of high-frequency neuromuscular electrostimulation with external weights in patients with chronic obstructive pulmonary disease with severe symptoms of shortness of breath and dysfunction of lower extremity muscles: a pilot effects study.

The aim of this study is to determine whether external weights affect the intensity of NMES and the possible effects on metabolic processes and muscle activity in COPD patients.

Intercostal nerve cryoablation versus thoracic epidural analgesia for minimal invasive Nuss repair of pectus excavatum: A protocol for a randomized clinical trial (ICE trial)

Primary objective of the current study is to determine the impact of intercostal nerve cryoablation on postoperative length of hospital stay compared to standard pain management of pectus excavatum patients treated with the minimal invasive Nuss…

Effects of COVID-19-infection on movement and tissue characteristics of the diaphragm visualized by magnetic resonance imaging: a proof-of-concept study

The primary goal is to evaluate the difference between diaphragm tissue characteristics and movement in extubated COVID-ICU patients after >72 hours of invasive mechanical ventilation compared to other ICU-patients and healthy controls.…

Optimal postoperative chest tube and pain management in patients surgically treated for primary spontaneous pneumothorax; a randomized controlled trial.

Our objective is to compare the efficacy of early chest tube removal combined with single-shot PVB versus standard treatment (chest tube for at least 3 days and thoracic epidural analgesia (TEA)) after surgery for PSP. Efficacy is defined as proving…