55 results
The aim of the study is to compare magnesiumhydroxide and polyethylene glycol/electrolytes with regard to the prevention of constipation and side-effects in palliative care cancer patients starting with opioids.
To determine the improvement in symptoms of constipation in subjects receiving treatment with oxycodone/naloxone prolonged release tablets (OXN) compared to subjects receiving oxycodone prolonged release tablets (OXY) based on the Bowel Function…
In this study we aim to determine the esophageal sensitivity by means of weakly acidic solution and esophageal distension, and determine the position and composition of the acid pocket in patients with and without PPI. We hypothesize that these…
Earlier studies suggest that Gaviscon alters the position of the acid pocket, as the number of acid reflux episodes decreased but the number of nonacid reflux events almost doubled after drug intake. (8) However, until now the formation of the raft…
To identify chromosomal regions associated with the GERD-phenotype in a large multigenerational family with multiple affected members. Subsequently these regions will be sequenced to detect causative gene(s). The second aim is to describe the…
Therefore, the aim of this study is to determine whether differences in EGJ distensibility lead to different rates of esophageal reflux by comparing EGJ distensibility with esophageal reflux characteristics, esophageal pressure characteristics and…
We aim to investigate the reflux characteristics in patients with LPR and healthy controls using pH/impedance measurements. A second analysis will be to compare total number of proximal reflux events in PPI responders and non-responders.
the aim of the current pilot investigation is to examine the effectiveness of mindfulness based stress reduction in reducing stress levels in IBS patients, as well as the effects of the training on IBS symptom severity and quality of life in these…
We hypothesise that the increased permeability of the esophageal mucosa in GERD patients can be shown using confocal laser scanning fluorescence microscopy. This difference in esophageal permeability may prove a diagnosticum for patients without…
To study the diversity and functionality of intestinal microbiota of patients with IBS over time in comparison with asymptomatic controls.
To investigate the influence of left and right lateral position on the onset of TLESRs and GER and the underlying mechanisms during and after a test meal in GERD patients compared to healthy controls.
Our Objective is to show that the administration of prokinectics leads to an altered position of the acid pocket scintigraphically, and it thereby changes the rate of postprandial acid reflux episodes.
The aim of the study is to assess the cost-effectiveness of implementation of tube feeding in hospitalized IBD patients.
Primary:- To identify causal genetic variants and proteomes involved in achalasia and to study their relevanceSecundary:- To build-up a large scale harmonized biobank of achalasia patients, based on combining existing and new data from the European…
This study has two main objectives:1. To assess the efficacy of hypnotherapy on symptoms and quality of life in IBS patients;2. To compare the efficacy of individual hypnotherapy with a group application of hypnotherapy in IBS treatment.
To compare the efficacy of POEM to the efficacy of endoscopic pneumodilatation as the initial treatment of symptomatic idiopathic achalasia. The treatment succes is defined as symptom relief based on a Eckhardt score of 3 or less at 3 months, 1 year…
The aim of this study is to measure and describe differences in manometric and impedance patterns in patients with an initial presentation of regurgitation and/or vomiting with and without clinical diagnosis of rumination syndrome. With these…
Evaluate which PEG (4000 or 3350) is most preferred by children.Evaluate whether a preferable taste of the drug can lead to a better compliance and subsequently to a better success percentage of the treatment of childhood constipation.
What is the normal stool frequency among premature and full term neonates?What is the normal colour of stools of the neonate?What is the normal consistency and amount of stools?What is the normal colonic transit time of premature and full term born…
The aim of this study is to compare the sensitivity of chromoendoscopy with Lugol*s solution with conventional white light video endoscopy in diagnosing esophageal dysplasia and cancer in patients with achalasia.