28 results
To assess and compare long term scar quality of deep dermal burns after debridement with hydrosurgical- and conventional tangential excision.
To determine long-term scar quality in patients admitted to a Dutch burn centre with burn wound of indeterminate depth.
To study wether a biodressing impregnated with polyhexamethylene biguanide in the treatment of spoke injuries in children could give a reduction in pain during the treatment compared to the standard treatment with wound dressing impregnated with
To obtain a comprehensive overview of long-term (*5 years after burn injury) consequences after burn injuries, both in all patients admitted to burn centre admissions and in a subgroup of patients who suffered from more extensive burns.
The goal of this study is to develope and validate a non-invasive method for the age determination of bruises. This method is tested on adult volunteers. We expect differences between the healing proces of bruises in adults and children.To be more…
The Activation of Coagulation and Inflammation in Trauma (ACIT) study is designed to identify the clinically significant mechanisms and pathways by which inflammation and coagulation are activated immediately following major trauma, and how these…
In this study we want to investigate if there are differences in cytokine and mFABp production when using a rigid and a soft-layered spineboard, in relation to tissue-interface pressures. Furthermore, redness of the skin and experienced comfort are…
Objective: The main objective is to evaluate the difference in scar quality, after skin restoration of full thickness defects treated with Glyaderm® and STSG versus STSG alone.Secondary objectives are: to evaluate the percentage of Glyaderm® take…
The primary objective of this study is to evaluate if there are differences in the tissue-interface pressures, pressures inside the tissues and tissue deformation in the sacral area when volunteers lie on a regular spineboard versus a vacuum…
To gain insight in the effects and cost-effectiveness of the introduction of laser Doppler imaging in burn care.
Primary objective: to investigate the possible role of FABP/Claudin levels as a diagnostic marker for significant intra-abdominal injury (necessitating therapeutical intervention).Secondary objective: to establish the use of plasma levels of I-FABP/…
We want to study whether there is a difference with respect to the pressure exerted onto the body when using a normal spineboard and a newly developed spineboard, related to the level of consciousness of the volunteer. Also the experienced comfort…
1. To assess the feasibility of a new treatment protocol of skin grafting of the burned dorsal hand in fist position with wrist in 30° flexion per and post ok.2. To explore the effects of skin grafting on the burned dorsal hand in fist position with…
To test the hypothesis stated above, we propose to study the dose-response relationship between various chemostimulants and PMN functions of major trauma patients and patients undergoing major surgery in vitro, both early after the initial trauma or…
The current study aims to gain better insight into the pathophysiology of the aberrant inflammatory response in CRPS. The evaluation of the role of pro-inflammatory and anti-inflammatory mediators in response to a microtrauma may generate important…
The main objective of this multicentre interdisciplinary study is to systematically aggregate data on moderate and severe traumatic brain injury patients in a national database. This database will serve to:a. get an estimation of the incidence of…
Aim of this study is to investigate the level of functioning and the quality of life of children and young adults, six to eight years after major trauma.
The primary objective of this project is to demonstrate the equivalence of treatment of traumatic splenic injury with splenic artery embolization (SAE) compared to splenectomy and non-operative management (NOM) in terms of quality of life measured…
To determine the accuracy and robustness of this method it is necessary to validate it. In the past some successful studies have been performed in adult volunteerd. However we would like to investigate the influence of induced changes to the healing…
To determine the accuracy and robustness of this method it is necessary to validate it. In the past some successful studies have been performed in adult volunteerd. However we would like to validate the model based on bruises that where induced with…