27 results
The primary objective is to assess bone structure parameters and bone strength by high resolution peripheral quantitative CT evaluation (HRpQCT) and physical activity in relation with subsequent falls, fractures and mortality in patients with a…
The first objective of this study is to evaluate the effect of standard HD with different dialysate calcium concentrations as well as HD combined with citrate-acid dialysate on the clearance of CPPs and second the effect of these different solutions…
The objective of the study is to investigate vertebral bone marrow fat fraction and bone mineral density during surgery induced weight loss.
To investigate the dynamic changes in bone marrow adiposity during the menstrual cycle as assessed by Dixon*s Quantitative Chemical Shift Imaging (QCSI) measurements and to determine the role of estrogen in these changes.
Onset of effect of systemic therapy to enhance bone density (eg, bisphosphonates) is not immediate and may not adequately protect subjects with decreased bone density from fracture.Bisphosphonate therapy will typically require 2 to 3 years of active…
The objective is to study the effect of beta-agonist and beta-antagonist treatment on human bone remodeling.
We examine whether the calcium intake from food in postmenopausal women with an ID suffice to the quantity calcium intake that is advised by the NHG-standard. If the conclusion of this study will be that the population is eating less calcium than is…
To study the effect of high dose oral cholecalciferol suppletion on serum 25-OHD in elderly with osteoarthritis of the hip.
The objective of this study is to assess the diagmostic accuracy of microMRI to detect ROD in children with ESRD and metabolic bone disease by oxalosis in patients suffering from oxalosis.
To assess whether a change in BMD as detected big DXA (gold standard) is comparable with the decline measured by the achilles method
Primary objective1.To determine the characteristics, frequency and severity of vascular, metabolic and hormonal side effects of angiogenesis inhibitors and EGFR inhibitors.Secondary objectives1.To investigate if steroid profile, indol profile,…
The aim of this study is to assess the sensitivity, specificity and predictive value of the Dutch osteoporosis case-finding instrument as a tool for vertebral fracture case-finding in a primary health care setting. Furthermore the impact of a…
A pilot study the effect of high dose oral cholecalciferol suppletion on serum 25-OHD in elderly with osteoarthritis of the hip.
The aim of this study is to determine the quantity of vitamin D3 in anterior adipose tissue in pregnant women, and to determine the influence of exposure to sunlight and the consumption of fatty fish on vitamin D storage in anterior adipose tissue.…
To demonstrate the feasibility to induce an effective, predictable and sustained decrease in FGF23 level in CKD stage I-IV patients, without inducing hypophosphatemia using a stepped treatment regimen aiming at restricting phosphate uptake.
The search for correlations between components of the diet and the group has experienced a hip fracture. These findings are compared with healthy elderly. The results can contribute to nutrition -focused interventions in future studies .
Objective: To obtain data to be used for designing a larger scale study on the incidence of 25OHD levels below the recommended level of 50 nmol/l in children in Murmansk, Russia and Groningen, the Netherlands.
This study aims to determine the effect of nocturnal versus daytime cyclic infusion of parenteral nutrition in adult chronic intestinal failure patients on bone turnover, glucose metabolism, nitrogen balance, sleep and wake rhythm and clock genes…
Clinical feasibility of the urine collection device, indicated by staff and parents.
This study has been transitioned to CTIS with ID 2024-519705-36-00 check the CTIS register for the current data. The primary objective will be to investigate if a two-year course of TPTD followed by antiresorptive treatment with a single infusion of…