42 results
In this randomized study, timing during (day 1-7 of the menstruation cycle WITH vaginal blood loss) or beyond menstruation (in menstruation cycle day 8 and further WITHOUT vaginal blood loss) will be compared regarding differences in patient-…
Main objective of this study is describing the functional morphology of the microcirculation of the endometrium.
To investigate whether it is possible to manipulate perfusion in type 3 fibroids with MR-HIFU.
To determine which advanced image enhanced modality is the most feasible for the detection of endometriosis lesions, with respect to the specificity and sensitivity of the investigated modalities. To determine which imaging modality reveals more…
To compare vascular density and angiogenic factors in normal endometrium and endometrium covering submucous fibroids in patients with submucous fibroids.
The purpose of this study is to quantify the amount of menstrual bleeding in participants with menorrhagia and its correlation to the overall impact of health as measured by the Menorrhagia Questionnaire.
Primary Objective: To assess whether the combination of Saline Infusion Sonohysterography (SIS) and Endometrial Brush Biopsy (EMB) will create an innovative algorithm for diagnosing corpus uteri malignancy in postmenopausal women suffering from…
Main: Investigate the cyclic variation in clot lysis time in women with HMB in comparison to controls. Secondary:- Investigate the cyclic variation in TAFI, PAI-1, tPA, PI, thrombin generation, fibrinogen, fibrin clot permeability and confocal…
To establish the safety and effectiveness of the Sonata System in the treatment of symptomatic uterine fibroids.
To obtain the safety and effectiveness data necessary to support a Premarket Approval (PMA) Application to the U.S. Food and Drug Administration (FDA)
We plan to compare the costs and effects of both methods.
To determine the feasibility of Fusion MRI-ultrasound for the uterus and ovary.To determine if Fusion MRI-ultrasound is more accurate for the diagnosis of endometiosis then MRI or ultrasound alone.
The purpose of the study is to evaluate the effectiveness and acceptability of the hot fluid balloon endometrial Thermablate ablation system compared with the Bipolar RF Novasure ablation treatment performed in an outpatient setting in eliminating…
To study if a hysteroscopic resection a safe and effective treatment is for intermittend/post menstrual bloodloss or spotting.
This study primarily aims to get insight in the intraoperative nociceptive state of the patient as an index of the amount of pain stimuli comparing the three modes of hysterectomy. Next to this, by measuring pre-, intra- and postoperative stress…
Primary Objective: test the feasibility of Dynamic-CE-MRI using Ablavar ® as contrast agent to detect peritoneal endometriosis in women.Secondary Objective(s): # To assess the image quality of Ablavar ®-enhanced MRI in comparison to unenhanced MRI…
- To assess the effect of QBW251 on the pharmacokinetics of a monophasic combined oral contraceptive containing 30 µg ethinyl estradiol (EE) and 150 µg levonorgestrel (LVG).- To assess the effect of QBW251 on the pharmacodynamics of a monophasic…
- To establish the bioequivalence of the hormones norgestimate, norelgestromin, and ethinyl estradiol in NGM/EE Schaffhausen tablets compared with the same hormones in NGM/EE Manati tablets.- To assess the safety and tolerability of both…
The primary objective of this study is to evaluate the safety and effectiveness of Doppler guided Uterine Artery Occlusion (D-UAO) as treatment for the reduction of fibroid-associated symptoms.
Ultrasonography shows a niche at the site of the uterine caesarean scar in the majority of women with a CS in the past history. A niche is a triangular, anechoic area at the presumed site of incision. Our primary objective is to develop an…