42 results
Primary Objective: Pilot study to identify the optimal patch test concentration for detecting contact allergy to ME-PPD in subjects with a proven contact allergy to PPD, who may be allergic to ME-PPD. Hypothesis: In this study subjects will be…
To assess visibility of standardized induced bruises using imaging (photography) under white light, forensic light sources, and multispectral scanning, at set time intervals.To gain understanding in the influence of individual factors on bruising.
Determination of volume and surface area of intramuscular oil depots during body clearance using MRI
The aim of this research is to determine the surface area of an oil depot during oil clearance. This is relevant for the release rate and therefore for the absorbed amount of active substance in blood. The volume is important for the interstitial…
The objective of this study is to compare two different anesthetic techniques in patients with an injury to the finger which requires anesthesia: traditional dorsal digital block and volar block. Primary objectives:- What is the difference in…
Primary objectives: Evaluation of the efficacy of imiquimod 5% cream compared to treatment with Large Loop excision of the transformation zone (LLETZ) for recurrent/residual CIN.Secondary objectives: evaluation of the effect of treatments on HPV DNA…
The generic objective of the study is to explore associations between exposure to livestock farms and potential health effects. This study will focus on 1) respiratory health effects, 2) Livestock associated infections (zoonoses), 3) Carriage of…
The primary objective of this study is to compare the prevalence of delirium between oxycodone and morphine, administered by CSCI, for the treatment of pain in dying patients with a diminished renal function.The secondary objective is to compare the…
Primary: To determine the effects of MIH on circulatory, inflammatory and metabolic aspects of host response to sepsis.Secondary: To determine if MIH prevents and/or decreases the severity of ICU-AW in septic shock.
-The primary objective is to compare the CYP2D6 phenotype, determined by DM-BT in frail and non-frail elderly (by using Fried definition).-The secondary objective is to correlate individual parameters of frailty (e.g. grip strength) with CYP2D6…
Comparing the OptiClose® System with traditional skin wound closure with intracutaneous sutures on wound closing time, patient comfort, cosmetic results, surgical handling, and costs.
The effectiveness of PRP treatment in patients suffering from chronic lateral epicondylitis is still ambiguous. Therefore we study PRP treatment in a double blind randomized controlled trial in a homogeny patient population with respect to duration…
The primary objective of this pilot study is to determine the effectiveness of four treatment options for local skin reactions induced by continuous subcutaneous apomorphine infusion, as compared to no treatment.The primary endpoint is the measured…
To study dose-dependent hemodynamic and microcirculatory changes during oxygen supply in mechanically ventilated ICU patients.
In this study we want to investigate if there are differences in cytokine and mFABp production when using a rigid and a soft-layered spineboard, in relation to tissue-interface pressures. Furthermore, redness of the skin and experienced comfort are…
This health care evaluation study will compare the ZPH with other, usual forms of care given to frail elderly in the hospital. It will also evaluate the added value of a centre for prevention and recovery (Centrum voor Preventie en Herstel, CPH)
The primary objective of this study is to evaluate if there are differences in the tissue-interface pressures, pressures inside the tissues and tissue deformation in the sacral area when volunteers lie on a regular spineboard versus a vacuum…
The primary aim of this study is to gain more insight on the impact of reconstructive surgery on circumcised women (type I, 2 & 3). This study may also used for theorizing about plastic surgery on women who are circumcised.
Objective: Determination of cross-reactivity to a newly developed PPD-derivative (F000175918) in previously PPD-sensitized patients. Hypothesis:Since PPD-derivative F000175918 is categorized as a moderate sensitizer, based on pre-clinical…
The objective is to investigate whether environmental exposure to livestock farm emissions in the Netherlands poses a health risk among neighbouring residents.
To show the differrence of total healing of wound between two therapies, VAC and gauze-therapy, in patient with a sinu pilonidalis after chirgical intervention.