16 results
The primary objective is to evaluate the difference in 68Ga-exendin tracer accumulation in the pancreas of patients with and without complete resolution of T2DM after RYGB by quantitative analysis of PET images.
The main objective is to examine if 68Ga-exendin tracer accumulation (i.e. beta cell mass) differs in patients with persisting HH after RYGB compared to matched patients without HH after RYGB. The secondary objectives are:- compare GLP1 and GIP…
This pilot study aims to explore whether and why the cardiorespiratory fitness is compromised in newly diagnosed patients with early Relapsing Remitting Multiple Sclerosis (RRMS) with no or minimal clinical symptoms (i.e. Expanded Disability Status…
To assess the impact of adding FFRct analysis to CCTA on the rate of unnecessary invasive coronary angiography (ICA) in patients with stable chest pain that have a >=50% but less than 90% anatomical stenosis on CCTA in any major epicardial…
To ascertain differences in mitochondrial and microcirculatory parameters between healthy older adults (> 65 years and ASA1-2) and more vulnerable elderly patients (> 65 years and ASA 3-4).
The objective of this study is to demonstrate that arthroscopic synovectomy of the wrist comined with deposition of intra-articular corticosteroids (DIACS) will lead to better functional outcomes compared to intra-articular corticosteroid injection…
The primary end-point is ipsilateral invasive breast tumor-free rate at 10 years. Secondary end-points are among others: overall survival, breast cancer-specific survival, mastectomy rate and patient reported outcomes.To determine whether low- risk…
The aim of this project is to identify biomarkers and novel therapeutic targets for pediatric Hodgkin lymphoma. To achieve this aim we defined three objectives:1.Hodgkin Reed-Sternberg cells: To perform whole exome sequencing and gene expression…
The overarching aim of this study is to develop new, sensitive measures for aspects of social cognition (emotion experience, empathy and affective theory of mind), that will contribute to a better and earlier diagnosis of specific subtypes (the…
The key objective of this study is to determine the clinical significance of using MRI scans as a diagnostic tool to assess velopharyngeal insufficiency in cleft palate patients.
Primary Objective: To prove that in patients with multivessel coronary disease (MVD) (>= 2 lesions with diameter stenosis >=50%) a PCI revascularization strategy based on revascularisation of all lesions presenting a vulnerable plaques…
This study will investigates the effect of high dose alkylating chemotherapy compared to standard dose chemotherapy as part of a multimodality approach in patients with oligometastatic HRD positive and/or BRCA1/2 related breast cancer.
The study objective is to measure beta cell mass and function in subjects with type 1 diabetes during and shortly after the honeymoon phase, to determine whether the change in metabolic control is mainly caused by a decrease in the total number of…
The main objective is to compare overall survival of an active surveillance approach to that of standard surgery for patients with either squamous cell- or adenocarcinoma of the oesophagus or oesophago-gastric junction
The primary objective is to perform a clinical validation of the analytical method for dried blood spot microsampling of cabozantinib, pazopanib, sunitinib, Lenvatinib, nivolumab, ipilimumab, pembrolizumab, atezolizumab or bevacizumab. The secondary…
The primary objective of the study is to investigate the medium to long term effects of replacing the conventional CXR exam with an ultra-low-dose CT in terms of patient health.Secondary outcomes are measures are • Quantity and type of follow-up…