43 results
In the current study, we want to demonstrate Rienso uptake in the vessel wall in patients with cardiovascular disease and relate the uptake of Rienso to endothelial permeability.
Primary Objectives:A. To assess the reproducibility and variability (interscan, intra- and interreader) of novel (DCE-)MRI techniques to measure vessel wall dimensions, wall shear stress and vessel wall permeability in healthy and cardiovascular…
The main goal of this study is to assess the difference in local pulse wave velocity measured at three different points in the left and right carotid artery in healthy subjects and in patients with symptomatic and asymptomatic carotid plaques. As…
Objectives: Part 1) To assess the prevalence of PA in general practice (part 1 of this study);Part 2) To describe differences of cardiorenovascular damage in newly diagnosed hypertensive patients with versus without PA (part 2 of this study);Part 3…
The primary objective is to assess the difference in absence of binary restenosis rate of endovascular treatment of intermediate and long lesions of the superficial femoral artery with the Legflow® PEB and nitinol stent, when compared to uncoated…
To determine the difference in EGG patterns in a fasting state and after a test meal between healthy controls and patients suffering from splanchnic ischemia (both single and multiple vessel stenosis). We hypothesize that patients with splanchnic…
The aim of this study is to investigate if changes in vascular compliance in children with type 1 diabetes are related to endothelial markers and to changes in skin AGE and to investigate whether patients at risk to develop cardiovascular disease…
To compare the confidence of the interventional radiologist in diagnosing and treating arterial stenoses and occlusions by digital subtraction angiography with contrast concentrations of 300, 240 and 140 mg iodine per ml. Also, we will compare the…
Ascertain feasibility, study burden, between-subject and within-subject variability of automated RH-PAT measurements in paediatric renal transplant recipients. Comparison of adipokines and inflammatory profiles in renal transplant recipients and…
To investigate whether 7T 31P magnetic resonance spectroscopy (MRS) provides an objective method to assess metabolic changes in response to ischemia in calf muscles of patients with critical limb ischemia (CLI) compared to healthy controls.Research…
To predict the risk of particular coronary plaques to cause myocardial infarction
Primary objective: To investigate whether urine prothrombin fragments are increased in individuals suffering from VTE (i.e. PE or DVT) or a myocardial infarction compared to healthy matched controls.Secondary objective: to investigate whether…
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Objective:The hypothesis of this study is that laboratory markers for blood coagulation, platelet activity and inflammation may help to identify patients at risk for a recurrent cardiovascular event after ACS. Secondary, we expect to find…
Our primary objective is to measurec glycocalyx volume with OPS imaging, before and after sublingual nitroglycerine-spray administration, in patients with premature atherosclerotic disease before the age of 40 years and a positiev family history for…
In this investigation we want to regain more insight in the cardiovascular risk profile of RA patients. Also we want to find out which patients should have more attention concerning their cardiovascular risk profile and probably therapy for…
The objective of this study is to to develop a selective and non-selective whole brain ASL perfusion stress test and at 3.0 Tesla based on ASL flow territory measurements.
To investigate the relation between premature cardiovascular disease and glycocalyx perturbation
To study the effect of transient high blood glucose level on the brachial artery FMD response, and to determine the reproducibility of the measurements and observed effect.
We hypothesize that intracranial vessel wall atheromas are an important underlying cause of middle cerebral artery obstruction. To test our hypothesis we will perform high resolution intracranial vessel wall imaging with a 7.0 Tesla MRI scanner in…