Search for a trial

Implantology and Sjögren*s syndrome: a multicenter prospective cohort study

To investigate changes in marginal peri-implant bone loss and the clinical performance of dental implants in SS patients compared to implants in healthy patients.

Mandibular Advancement Device (MAD) therapy in edentulous patients with obstructive sleep apnea: dental implant fixed MADs vs. CPAP.

The main purpose of this pilot study is to assess the feasibility and potential efficacy of implant retained mandibular advancement device (MAD) therapy on a small scale in edentulous patients with mild to moderate OSA in comparison to CPAP therapy…

Bèta-TCP (bèta-tricalcium phosphate) as a bone substitute in patients undergoing repair of the alveolar cleft in CLP(Cleft Lip Palate) patients.

This current study aims to investigate the use of Curios bèta-TCP, a synthetic tricalcium phosphate for repair of the alveolar cleft in patients with clefts of lip, alveolus and palate.The specific properties of Progentix TCP result in optimal and…

A multi center, prospective, randomized controlled trial comparing cervical arthroplasty to anterior cervical discectomy and fusion (ACDF) for the treatment of cervical degenerative disc disease.

The primary objective of this investigation is to evaluate the performance of the DISCOVER Artificial CervicalDisc in the treatment of cervical disc disease by measuring the function assessed via Neck Disability Index(NDI) and neurological function…

Taste, Speech and oro-facial relations following partial tongue reduction: A single-center, longitudinal, functional outcome study in patients with Beckwith-Wiedemann Syndrome that have undergone tongue reduction surgery

The aim of this study is to investigate the long-term outcomes in patients with BWS that have been surgically treated at our institution with the help of simple, non-invasive, objective study tools. We hope to gain valuable information regarding the…

Conventional tonsillectomy versus outpatient CO2-lasertonsillotomy in adult patients; a randomised controlled trial

The purpose of this study is to demonstrate the effectiveness of treatment using the CO2-laser in one selected group of patients compared with a classical tonsillectomy. We also compare peri-operative en post-operative morbidity, pain, complications…

A Randomised Controlled Clinical Trial comparing the results of the Immediate Loading (within 48 hours) of Mandibular Overdentures supported by either 2 standard Straumann dental implants or 4 Mini Dental Implants (MDIs).

In this randomized controlled clinical trial we aim to apply the-already investigated-concept of immediate loading protocol and examine the performance of implant-retained overdentures using 2 SLAactive Straumann implants connected by bar ( Contol…

Cervical spine movement, before and after anterior cervical discectomy (ACD).
ACD, pure intervertebral discectomy (1) compared to intervertebral discectomy followed by implantation of an intervertebral disc prosthesis (2) in patients with a radicular syndrome. A randomised study

Objective of the study is to verify whether the movement pattern after anterior cervical discectomy normalises, in case of implantation of a cervical disc prosthesis.

Bilateral Cochlear Implantation Benefits in Adult Users of the HiRes 90K Bionic Ear System

1) Compare a group of bilateral users to a unilateral control group (between-subject design)2) Compare unilateral use to bilateral use after sequential implantation (within-subject design)3) Compare simultaneous bilateral implantation to sequential…

Biodegradable polyurethane foam modified with 55% polyethyleneglycol as a local hemostatic agent, a pilot study.

Goal of this study is to asses the feasibility of polyurethane foam as a local hemostatic agents in sockets after dental extraction. The assessment will take place in a small number of patients. After the pilot study, a large study will be…

The use of β-TCP (bèta-tricalcium phosphate) as a filler of the autologous symphyseal bone graft harvest site in patients undergoing grafting of alveolar clefts in CLAP(Cleft Lip Alveolus Palate) patients

This current study aims to investigate the use of bèta-TCP, a synthetic tricalcium phosphate, as a filler of the autologous symphyseal bone graft harvest site in patients undergoing grafting of clefts of lip, alveolus and palate.The specific…

Alveolar ridge preservation with a xenograft Bio-Oss Collagen) and a collagen matrix (Mucograft Seal) or a free connective tissue graft versus spontaneous healing: a 1-year prospective randomized clinical study

To evaluate clinical and esthetic outcomes and patient satisfaction following single-tooth replacement in the anterior maxilla in patients treated with a collagen matrix (Geistlich Mucograft® Seal) and a free connective tissue graft versus…

Implant supported maxillary overdentures in the augmented maxilla: 4 versus 6 implants

Primary Objective: The objective of this study is to asses whether or not the use of four implants in the augmented maxilla is as effective on the improvement of the patient*s oral functioning measured with the MFIQ as the use of six…

Single-stage bone-anchored hearing implant surgery in the pediatric population using the BHX implant

To compare implant loss between single-stage BAHI surgery (test group) and two-stage BAHI surgery (control group) in children. Furthermore, to compare soft tissue status, time to loading and duration of surgery between groups.

Comparison of the sagittal split osteotomy with and without defined inferior mandibular border osteotomy

Primary Objective: The hypothesis of this study is that an Obwegeser Dal Pont splitting procedure with a well- defined inferior border osteotomy needs less torque to split the mandible than the traditional technique.Secondary Objectives: Using the…

The enrichment of the fat graft in facial fat grafting for increased volume retention

The comparison of standard fat grafting with enriched fat grafting.

Transoral robot surgery of the tongue base vs. Continuous positive airway pressure or mandibular advancement device as a treatment for moderate to severe obstructive sleep apnea.

The primary objective of this study is to objectify the efficacy of TORS compared to CPAP and MAD. Secondary objectives:To determine long term outcomes of TORS compared to CPAP or MAD.To compare functional sleep outcomes in TORS and CPAP/MAD…

Improving accuracy of genioplasty in orthognathic surgery with a patient-specific guidance system: a randomized intervention study

The main objective is to determine if the application of a patient-specific guidance system improves the accuracy of the genioplasty. The secondary objective is to assess the effect of the application of patient-specific guidance system on the…

Single-stage bone-anchored hearing implant surgery in the pediatric population using the BI300 implant

To compare implant loss between single-stage BAHI surgery (test group) and two-stage BAHI surgery (control group) in children. Furthermore, to compare soft tissue status, time to loading and duration of surgery between groups.

Topical haemostatic agent Arista* AH compared to nasal packing following turbinate surgery: a prospective randomised controlled trial.

The main objective of this randomised controlled study is to investigate whether patients treated with Arista* AH have less postoperative complaints after inferior turbinate surgery compared to patients treated with non-absorbable Merocel® nasal…