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A randomized controlled double-blinded trial comparing the effect of on demand rocuronium boluses vs continuous infusion on rating of surgical and anesthesia conditions and need for reversal in patients undergoing thoracolaparoscopic esophagectomy.

Primary objective is to evaluate the use of deep muscle relaxation versus on indication only on surgical and anesthesia conditions in patients for endoscopic esophageal resection.Secondary objective is to evaluate the (hypothetical) dose of…

Recurrence rate of hiatal hernia repair with biomesh compared to repair without mesh * a double blinded, randomized, controlled trial.

The above mentioned literature shows that repair of a hiatal hernia using a mesh gives fewer recurrences than repair without mesh. However, there are few prospective randomized controlled trials that provide clear results about this. The most…

Vitamine suppletion by morbide obase patient

Optimization of the supplementation of vitamins and minerals1. In patients who received a gastric banding for treatment for their morbid obesitya. Reduction of iron deficiencyb. Reduction of Vitamin B12 deficiencyc. Reduced Vitamin D deficiency2. In…

The Anal Fistula Plug versus the fistulotomy for the treatment of low perianal fistulas

To compare the Anal Fistula Plug with the fistulotomy in the treatment of low perianal fistula.

Valvuloplasty as alternative to Toupet fundoplication for the minimal invasive treatment of gastroesophageal reflux disease: a randomized controlled trial

This monocenter randomized controlled trial aims to compare postoperative outcomes of a laparoscopic valvuloplasty with a Toupet fundoplication in patients with GERD with a maximum hiatal hernia of 3cm. In addition, an economic evaluation of the new…

Tailoring Limb length based on total small bowel length in omega-loop gastric bypass

To investigate whether adjusting the length of the BP-limb of the OAGB based on measured total small bowel length leads to more weight loss, resolution of co-morbidities with less development of micronutrient deficiencies and bowel movements…

The effectiveness of adding Braun anastomosis to Standard Child reconstruction to reduce delayed gastric emptying after pancreatoduodenectomy (REMBRANDT): a multicenter randomized-controlled trial.

To assess the effectiveness of adding BE in reducing DGE in patients undergoing open pancreatoduodenectomy.

The Anal Fistula Plug versus the mucosal flap advancement
for the treatment of Anorectal Fistula

To compare the Anal Fistula Plug with the mucosal flap advancement in the treatment of high perianal fistula in terms of success rate, continence, postoperative pain and sick leave.

Distal pancreatectomy, minimally invasive or open, for malignancy (DIPLOMA)

To compare MIDP with ODP regarding radical resection rate) for pancreatic ductal adenocarcinoma (PDAC) in the pancreatic body or tail.