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Exploring the use of optical coherence tomography and hyperspectral imaging in glioma detection during surgery

Primary Objective: To assess whether both OCT (optical coherence tomography) and/or HSI (hyperspectral imaging) detect differences in glioma tissue as compared to healthy tissue as examined during brain-surgery.Secondary Objective(s): To assess if…

Sensation in children with an Obstetric Brachial Plexus Palsy

The main objective is to investigate if the sensation of children with an upper OBPL is diminished. Both children that were treated conservatively as children that were surgically treated with nerve surgery in early infancy.The primary research…

Measuring Vestibulo-Ocular Reflex in three dimensions

The objective of this study is to examine the vestibular system in three dimensions. To achieve this goal three experiments are performed. The EyeSeeCam video-oculography is validated with the scleral search coils (international golden standard).…

(Cost) Effectiveness of Surgery versus Prolonged Conservative Treatment in Patients with Intermittent Neurogenic Claudication caused by Lumbar Stenosis

Intermittent neurogenic claudication due to lumbar stenosis is frequently diagnosed among older persons. Due to an aging population it is to be expected the incidence of lumbar stenosis will increase over time. Patients are operated on because of…

Viscosity of PMMA Bone Cement in Percutaneous Vertebroplasty for Osteoporotic Vertebral Compression Fractures: A Randomized Controlled Trial

Establishment whether usage of high viscosity PMMA bone cement in PVP for OVCFs leads to a reduction in leakage incidence compared to usage of conventional (low-medium) viscosity PMMA bone cement in PVP for OVCFs.Since evidence is scarce or…

Interbody fusion devices in the treatment of cervicobrachial syndrome; a blinded randomised trial of cancellous structured ceramic (CSC) versus PEEK cages.

To compare functional recovery of the patient and the fusion status of ceramic cages versus PEEK cages on the short and long term.

Prediction and recovery of cognitive impairment in neurosurgical patients.

[Retrospective clinical path:1) main objective: to identify predictors (sociodemographic, clinical, imaging, and (neuro)psychological variables) of objective cognitive functioning of all patients who undergo neurosurgyer, at 3 months after surgery2…

Glioblastoma targeted treatment option maximization by WGS (GLOW);Maximizing treatment options for recurrent glioblastoma patients by whole genome sequencing-based diagnostics

To determine the value of and generate the clinical evidence for routine application of Whole Genome Sequencing (WGS)-based diagnostics and targeted therapy guidance for glioblastoma patients at time of first recurrence.