53 results
To compare functional recovery of the patient and the fusion status of ceramic cages versus PEEK cages on the short and long term.
1. To implant a functional vestibular prosthesis using the ampullar *V*-approach, as developed in our own clinic.2. To investigate protocols for adjusting the vestibular implant (VI) to required settings, regarding:-- Modulation sensitivity--…
Our objective is to obtain insight into whether and how the visual and auditory systems of hemispherectomized patients have adapted after brain damage and brain surgery in early life. For this purpose we will perform psychophysical tests and (…
Primary objective is to study the number of patients gaining at least 50% pain reduction within 8 weeks following PRF as compared to following a neurectomy. Pain intensity will be measured using numeric pain rating score (NPRS, 0-10) and Verbal…
What is the cost-effectiveness of minimal invasive posterior lumbar interbody fusion in spinal stenosis patients, compared to the standard open fusion?
The primary goal of this study is to compare ultrasound-guided ANB with FHB for analgesia during closed reposition of distal forearm fractures. Secondary goals are evaluation of feasibility in the ED regarding time and procedure success rate.…
The objective of the study is to clinically assess the safety and effectiveness of LIQOSEAL® as a means of reducing intra- as well as post-operative CSF leakage in patients undergoing elective cranial intradural surgery with a dural closure…
To assess the impact of CBT on treatment outcome after lumbar spinal fusion surgery in patients with high pain catastrophizing, a two-center randomized controlled trial comparing CBT care to education.
To compare the (cost-)effectiveness of early surgical hematoma evacuation versus a conservative treatment in elderly patients with a traumatic ASDH.
To make an evidence-based recommendation on which method has the best efficacy (PROM), patient treatment experience (PREM) and safety profile (complications).
The aim of the study is to determine the accuracy of pedicle screw placement when using the iNav navigation tool compared with the established computertomography based navigation.
To determine if the incidence of adverse local events (local failure or radionecrosis) can be reduced with more than 20% using fSRT versus SRT in one or three fractions.
[Retrospective clinical path:1) main objective: to identify predictors (sociodemographic, clinical, imaging, and (neuro)psychological variables) of objective cognitive functioning of all patients who undergo neurosurgyer, at 3 months after surgery2…
The purpose of this post-approval protocol amendment is to extend the follow-up of subjects who were originally enrolled in theRCT, EUBARD-CP_001 protocol. This study extension will examine the long-term survivorship of the Barricaid® ACD when…
Research question(s). There are two specific questions to be addressed:1) Is percutaneous transforaminal endoscopic discectomy (PTED) no worse in effectiveness than conventional unilateral open microdiscectomy for patients with symptomatic…
To investigate if resection with a margin, that is significantly beyond the radiological contrast enhancement, improves overall survival in selected patients with glioblastoma.
Primary objective: To assess the effect-of initial DXM therapy versus primary surgery on functional outcome (as expressed by the mRS) and costs in patients with a newly diagnosed CSDH respectively after 3 and 12 months.Secondary objectives are:…
The aim of the proposed study is to examine whether ACDA compared to ACDF is preferable in terms of costs, effectiveness and utility from a hospital and a societal perspective.
There is a high degree of diversity in attributed risk on thrombosis in the neurosurgical patient cohort. Due to this diversity, insufficient power of performed studies and lack of careful phenotyping and description of risk factors in previous…
Identifying the (immune) cell composition, co-localization, functions, and alterations as well as blood and lymph vessels reorganisation in the human*s dura, arachnoid and pia mater, and skull bone marrow in high-grade glioma patients as compared to…