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Intracutaneous sodium storage in Intensive Care patients

To demonstrate differences in intracutaneous sodium storage between a control population, patients admitted after elective cardiothoracic surgery and septic patients.

Residual effects of Cushing*s syndrome after long term remission: Impact on adipose tissue, insulin resistance, exercise intolerance and increased risk of cardiovascular disease.

To identify some of the mechanisms in patients in remission of Cushing*s syndrome that contribute to the persistence of visceral obesity, systemic inflammation, insulin resistance, sarcopenia, a low muscle oxidative capacity and increased risk of…

Facial and hand analysis, sleep apnea and speech in patients with acromegaly: a prospective study to investigate changes in craniofacial and hand characteristics, sleep apnea and speech during treatment and after remission.

To investigate the changes in facial- and hand analysis in patients with acromegaly as a result of medical treatment and pituitary surgery, and to investigate the changes in relational proportions between facial- and hand structures, incidence and…

Exploring underlying mechanisms of paediatric growth disorders using human ex vivo growth plates.

The current study is designed to collect viable growth plate tissue of tall statured individuals that undergo percutaneous epiphysiodesis (PE). With this collected biomaterial we will be able to characterize dynamic changes in growth plate…

Disentangling the cause of atypical femur fractures associated with the use of bisphosphonates

Primary Objective: to identify risk factors and the underlying mechanism of AFFs by:- setting up a database with detailed information to define patients* characteristics.- building a biobank with urine and blood samples from these patients. -…