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The effects of nanoparticles and ambient particles on brain function using quantitative electro-encephalography (QEEG) in healthy volunteers

To investigate whether exposure to nanoparticles is able to induce short-term functional changes in the brain, we previously exposed human volunteers for one hour to diesel exhaust particulates (300 ug/m3) and followed their brain activity during…

Multi-locus approach in pharmacogenetics. Application in the cholesterol lowering and anti-inflammatory pathways of statins

The aim of this project is to study SNPs in genes involved in the cholesterol lowering pathway and in the anti-inflammatory pathway of statins to explain differences in the protective effect of statins against myocardial infarction (MI). A second…

The CRYSTAL study: CMR of intraventricular flow analysis and genetic phenotyping in Hypertrophic Cardiomyopathy (HCM): a roadmap for surgical myectomy

The primary objective of this study is to assess wall shear stress in the left ventricle outflow tract using 4D flow CMR in healthy controls, asymptomatic HCM and before and after surgical myectomy in patients with HOCM,