113 results
The purpose of this study is to determine whether early intervention with subcutaneous (s.c.) secukinumab 300 mg in patients with new-onset moderate to severe psoriasis may lead to prolonged symptom-free periods by preventing reactivation of old…
The main objective of this study is to investigate the effect of a topically applied emollient enriched with barrier lipids on the barrier properties of skin of AE patients.
The primary objective of this study is to compare the therapeutic effect on atopic dermatitis of a skin barrier repair cream (Dermalex eczema) in contrast to a standard used emollient (unguentum leniens FNA) and a dermatocorticoid (hydrocortisone)…
To compare the efficacy of alitretinoin and azathioprine in the treatment of severe chronic non-hyperkeratotic hand eczema.
Primary objectiveTo compare the efficacy of subpurpuric pulsed dye laser treatment with different intervals between treatment sessions.Secondary objectiveTo evaluate the safety and the long-term effects of subpurpuric pulsed dye laser treatment.
Scar volume and POSAS score will be measured in the Verapamil group, these will be compared to the scar volume and POSAS score in the Kenacort+Verapamil group and the Kenacort group. In addition, complications/ adverse effects will be reported.
To evaluate the additional effect of coal tar treatment to a corticosteroid regimen in adults (aged >16 years of age) with moderate to severe atopic dermatitis, based on the percentage change in Eczema Area and Severity Index (EASI) at week 2…
To investigate the acceptability and feasibility of exercise therapy in an aquatic environment by patients after burn injury.
Objective: We want to extend our understanding of the disease aetiology by performing a small pilot study that incorporates other immunologic sites involved in the disease (the skin and the microbiome) while additionally strengthening our disease…
Primary objective: To prospectively evaluate the lesion (AN-)count, i.e. abscesses, inflammatory nodules, and draining sinuses, in the axilla treated with MWA compared to the untreated contralateral axilla after six months.Secondary objectives: - To…
The main objective of our study is to examine whether there is an association between IT (as determined by visual irritation grading scale after SLS patch test) and HTS formation and whether IT is a good predictor for HTS formation. If so then this…
To determine the relationship between phenotypic, genetic and biochemical features of AD. , Relevant bimarkers of the skin barrier function including the levels of NMFs, inflammatory mediators (e.g. IL-1 cytokines), SC lipids and serine proteases…
To evaluate whether doxepin hydrochloride 5% cream is more effective in reducing pruritus in burn patients than standard treatment (clemastine).
A randomised controlled multcenter trial is performed to evaluate the perforator-based interposition plasty in comparison to full thichness grafts for scar contracture releases.
To assess the preemptive effect of Bepanthen® on decreasing the incidence of specific >= grade 2 dermatological side effects of interest in respect of compliance to EGFRI agents, HRQoL and the adherence during the 6-week skin treatment period…
The primary research question is:Do children with atopic dermatitis and asthma after a stay in the NAD have a better coping and acceptance of their disease as compared with children treated at the outpatient department of the WKZ?Secondary research…
To evaluate the effectiveness, cost-effectiveness and quality of life of Flaminal® versus Flammazine® in the treatment of superficial and deep partial thickness burns.
To test the suitability of OCT for in vivo imaging of the vascularisation and surrounding tissue of burn wounds and scars.
The main objective of the study is to determine whether induced nocebo effects (negative expectancy effects) for itch can be modified by a positive expectation induction. Secondary objectives are to explore: a) the effects of expectation inductions…
The primary objective of this study is to detect significant difference in the average response to histamine, topically and iontophoretically applied to the skin, between sensitive and non-sensitive skin volunteers. Skin reactions are assessed with…