30 results
1. Immunology and Pathology:To determine the immune response of patients with simple and complex appendicitis in order to identify markers which distinguish between simple and complex appendicitis.2.Clinical and Imaging:To analyze the differences in…
To determine the frequency of MBL and FCN SNPs in patients with a history of a proven gram-positive bacteremia, compared to patients without such history. A secondary objective is to determine whether extracorporeal circuits, used in cardiothoracic…
The aim of this study is to determine whether the presence and the extent of periodontitis are independently related to the presence and extent of coronary calcification.To determine if periodontal treatment has an positive effect on the…
To determine the presence of ACPAs in patients with generalized severe periodontitis. Second objective is to assess RA development of ACPA positive periodontitis patients in the future.
The main objective of this part of the study (Work Package 1, WP1) which is part of a n European Union funded FP7 project entitled EUCLIDS is to develop, maintain and regulate the clinical network required to collect clinical data and patient…
To determine the genetic risk of susceptibility to, or severity of community-acquired pneumonia by comparing the interpersonal genetic variation of the host immune response of patients with community-acquired pneumonia to healthy controls and by…
1. To determine, in patients treated with TNF α blockers and living in the Q-fever endemic area, the prevalence of antibodies against C. burnetii and the prevalence of chronic Q fever.2. To assess other determinants in this group of patients which…
Primary objective: To determine the effect of hyperbilirubinemia on systemic activation of the innate immune response induced by a lipopolysaccharide (LPS) challenge. Secondary Objective(s): - To determine if hyperbilirubinemia shifts the pro-anti…
The principal goal of this study is to identify whether and how innate immune host factors predispose to the development of chronic Q-fever.
The primary objective of the study is to identify the bacterial flora on the abutment in a phylum/species classification. The secondary objectives are to assess the relationships between the commensal skin flora and the flora on the abutment and to…
Investigation of the prevalence of sinonasal disease on CT-sinus in children with Cystic Fibrosis at different ages. This study will focus especially on the onset of sinonasal pathology in Cystic Fibrosis in relation to the development of the…
The objective of this study is to identify determinants, to determine the transmissibility and to determine the burden of disease of NT-MRSA and CA-MRSA carriage compared to other typeable MRSA strains in the community.
Primary objective: To determine the dynamics of MRSA carriage in persons working on or living at pig and veal farms.Secondary objectives: To determine the amount of disease associated with carriage of MRSA-CC398. To determine the role of exposure to…
This study aims to define the role of the IEC in S. aureus colonisation.
Establish relevance of a clinical scoring system, and of established and to be identified biomarkers in blood and urine for clinical course and clinical and microbiological outcome of patients with a complicated urinary tract infection, treated in…
Objective of this study is to investigate cytokine production and expression of toll-like receptors on monocytes in blood samples from pregnant and non-pregnant women using sonicates from different types of oral pathogenic micro-organisms and…
1. The primary aim of the study is to investigate whether periodontal treatment results in a decrease of plasma biomarkers that are related to cardiovascular diseases (CVD) and metabolic syndrome (MS) and what is the effect of the treatment on the…
To determine and compare the periodontal status between the different groups of women. Periodontal examinations will be performed within one week after delivery. If periodontal disease is diagnosed within the selected groups, it is plausible to…
To investigate the gene and protein expression of neonates suffering from CoNS late-onset sepsis.
This proposal will investigate how and which immunosuppressive agents affect the innate immune response against infection. Understanding the impact of immunosuppressive agents on TLR-signaling and TLR-control may be a new focus for the development…