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A Modified Case Control Study To Identify Pharmacogenomic Factors Associated With Hepatocellular Injury Following Exposure To Lapaquistat Acetate

To examine the genetic contribution to the mechanism of lapaquistat acetate induced hepatic abnormalities.

Epidemiology and natural history of and risk factors for primary sclerosing cholangitis & primary biliary cirrhosis in the Netherlands

Main objectives: To obtain true population-based prevalence and incidence figures, as well as insight in the natural history of PSC and PBC in The Netherlands.Secondary objectives: to determine risk factors correlated with PSC and PBC respectively,…