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CROSSFIRE trial: Crossatlantic Randomized controlled trial comparing Outcome in Survival after Systemic plus Focal therapy for Inoperable pancreatic carcinoma: Radiotherapy versus irreversible Electroporation

The objective of this study is to compare the efficacy of chemotherapy and IRE (experimental arm) to the efficacy of chemotherapy and radiation (control arm) in patients with locally advanced, non-resectable, non-metastasized, pancreatic cancer.