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PROGRESSIVE ESOPHAGEAL DILATION FOR BENIGN STRICTURES: A RANDOMIZED CONTROLLED TRIAL

The main objective is to compare the efficacy and safety of esophageal dilation with the balloon the Savary bougie dilator according to the rule-of-3 to rule-of > 3 strategy during 6 months in patients with a severe benign esophageal…

A RANDOMIZED COMPARISON OF DEGRADABLE ESOPHAGEAL STENT VS DILATION THERAPY: *DESTINY TRIAL* FOR PATIENTS WITH RECURRENT BENIGN ESOPHAGEAL STRICTURES

To compare the efficacy and safety of dilation of recurrent benign esophageal strictures by using a degradable self-expanding stent or standard dilation therapy.

Endoscopic Stenting versus Operative Intervention in Malignant Gastric Outlet Obstruction(STENTOP), a multi-center randomized controlled trial.

To investigate which treatment modality is preferable in patients with an irresectable malignant gastric outlet obstruction: endoscopic stent placement or a surgical gastrojejunostomy.

Clip-assisted duodenal feeding tube placement: a single blind, randomized controlled trial

To compare migration rate to the stomach or esophagus of clip-assisted endoscopic duodenal feeding tube placement with non clip-assisted endoscopic duodenal tube placement.

A randomized comparison of a fully covered self expandable metal stent versus a partially covered self expandable metal stent in malignant esophageal strictures

To compare a fully covered metal stent versus a partially covered metal stent in patients with dysphagia due to an incurable malignant stenosis of the esophagus or cardia.

A Multi-Center, Prospective, Randomized Study Comparing Removable, Self-Expanding Metal Stents to Plastic Stents for the Treatment of Benign Biliary Strictures Secondary to Chronic Pancreatitis

To compare the use of Self Expanding Metal Stents (SEMS) to plastic stents for the treatment of benign biliary strictures secondary to chronic pancreatitis as it pertains to stricture resolution rates, complication rates and number of ERCP…

Laparoscopic pyloromyotomy (LPM) vs open pyloromyotomy (OPM) for hypertrophic pyloric stenosis:
Is there a difference in the postoperative reconvalescence and the immunological response?

The aim of this study is to compare LPM with OPM with respect to clinical benefits or disadvantages of LPM in children with hypertrophic pyloric stenosis.

A Multi-Center, Prospective, Randomized (RCT) Study Comparing WallFlex® Esophageal Fully Covered (FC) Metal Stent to Bougie Dilation for the Treatment of Refractory Anastomotic Esophageal Strictures

To demonstrate that management of dysphagia for the treatment of refractory anastomotic esophageal strictures is more effective with Fully Covered metal stent than with Bougie Dilation.

Intensive endoscopic therapy versus conventional treatment for untreated benign anastomotic strictures after esophagectomy: a pilot and randomized controlled trial

To prolong the dysphagia-free period and to reduce the number of endoscopic dilations for patients with newly diagnosed, untreated benign anastomotic strictures after esophagectomy.

Needle-knife incision therapy compared to usual care of recurrent gastroesophageal anastomotic strictures: a multicenter randomized controlled trial (SAMURAI-study)

The aim of the current study is to evaluate the efficacy and cost-effectiveness of NKI followed by EBD compared to standard EBD in patients with recurrent esophagogastric anastomotic strictures. The combination of NKI and EBD is estimated to achieve…

Esophageal self-expandable metal stent for malignant strictures: an observational study

The aim of this study is to evaluate the safety and efficacy of the esophageal partially covered SEMS. We will pay specific attention to recurrent dysphagia rates, migration rates and pain.

A prospective randomized multi-center study comparing endoscopic pneumodilation and per oral endoscopic myotomy (POEM) as treatment of idiopathic achalasia

This study is designed to evaluate which of the two treatment modalities results in the highest success rate after 2 years. Thereafter, follow-up will continue and a similar analysis will be performed 5 years after treatment (and every 5 years…

Endoscopic ultrasonography-guided gastroenterostomy versus surgical gastrojejunostomy for palliation of malignant gastric outlet obstruction (ENDURO-study)

Primary objective:to investigate and compare the effect of EUS-GE and SGJ on patients* short- and long-term ability to eat* (time to oral intake, and reinterventions for persistent or recurrent symptoms of GOO within 6 months of follow-up,…

Colonic stenting as bridge to surgery versus emergency surgery for management of acute left-sided malignant colonic obstruction: a multicenter randomized trial (Stent-in II study)

To compare colonic stenting followed by elective surgery with emergency surgery for the management of acute left-sided malignant colonic obstruction in terms of health-related quality of life, morbidity and mortality.