11 results
As there are limited data on how to improve outcomes for those patients who do not benefit sufficiently from the availabletreatments, this study aims to compare MBCT to TAU as an adjunctive treatment to reduce depressive symptoms in patientswith…
Primary objective: Are changes in stress-induced autonomic and hormonal parameters associated with (epi)genetic vulnerability for schizophrenia and bipolar disorder?Secondary objectives: 1. Are changes in autonomic and hormonal parameters after…
The objective of this study is to include 200 cases, 200 unaffected first and second degree family members and 200 unrelated healthy controls to participate in the assessment of variability in activity and light exposure, as these domains are…
The main goal of this study is to recruit and obtain magnetic resonance images in a large sample of bipolar patients and controls from the Netherlands, in order to find brain abnormalities specific for bipolar disorder. We will also perform genetic…
We want to identify perception biases in bipolar patients with both depressive and hypomanic mood symptoms.
The primary aim of this study is to investigate if prophylactic pharmacotherapy peripartum is associated with a lower chance of relapse peripartum. In more detail, we will investigate if there is a difference in relapse between patients that used…
Objective: The primary objective is to examine whether EMDR therapy has mood-stabilizing effects in traumatized patients with mild depressive and/or manic symptoms. The secondary objective is to examine the hypothesis that EMDR is an effective and…
Primary Objective: To identify immuno-endocrine and neuro-imaging parameters differentiating between different mood states (manic, depressive, and euthymic). Secondary Objectives: 1. To identify the influence of these parameters on the onset and…
The primary objective is the extent and kind of cognitive deficits in patients suffering from bipolar disorders compared to healthy controls and patients with a lifetime diagnosis of unipolar depressive disorder. Secondary objectives specify the…
Our study aims to assess the effectiveness of a brief Imagery-focussed Cognitive Therapy (ImCT) compared to psychoeducation, regarded as treatment as usual for this patient population, in patients suffering from Bipolar Disorder. ImCT was…
Primary:- Investigate the feasibility of examining fetal and neonatal brain developmental trajectories in the fetus and neonate with at least one parent with SMI in the mood-psychosis spectrum (vs. parents without SMI) using MRI.- Acquire…