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Ammendment of protocol: Intravenous iron treatment in iron deficient patients with idiopathic pulmonary arterial hypertension. Title amendment: Skeletal muscle strength in healthy persons and patients with pulmonary hypertension

To evaluate the effects of intravenous iron suppletion in iron deficient PAH patients.Amendment: to compare exercise capacity and isolated muscle strength in IPAH patients and healthy controls

Evaluation of boiled vs raw eggs for stimulating post-exercise muscle protein synthesis

Looking into the effects of raw vs boiled eggs vs isocaloric low-protein meal on muscle growth.

A Study of Respiratory Muscle Strength, including Effort-Independent Measures, in Subjects with Late-Onset Pompe Disease

The primary objective of this study is to compare respiratory muscle strength values obtained using volitional techniques with values obtained using non-volitional techniques. The secondary objective is to compare the change for these two sets of…

Effect of Fecal Transplantation on Satiety, Sarcopenia, Inflammation and Chemotherapy Toxicity in patients with Metastasized Oesophageal and Gastric Cancer.

Primary objective:Effect of fecal transplantation (from healthy obese donors) on faecel microbiota composition in relation to satiety (questionnaires, biomarkers) and metabolism (REE ) in patients with metastasized or locally advanced oesophageal or…

The effect of neuromuscular electrostimulation on muscle strenghthening of the m. quadriceps and on physical performance in frail elderly with poor physical performance on <= day 4 of hospital admission. Pilot study.

In recent studies physical training against resistance appeared to be the most successfull to prevent sarcopenia. Because of the bad physical condition of the elderly during a hospital admission resistancetraining can't be applied. A Pilot…

A randomized, two-arm, prospective, subject blind study to assess the safety and efficacy of InSpace* device in comparison to full thickness massive rotator cuff repair in subjects scheduled for a repair surgery.

This is a post-marketing study to further assess the safety and efficacy of the InSpace* device implantation in comparison to surgical repair of full thickness MRCT . The efficacy will be assessed by comparing the pre- and post- operative shoulder…

Effectiveness and cost-effectiveness of Pain Rehabilitation Programs (PRP) for patients with chronic musculoskeletal pain: less is better?

To analyse the effect of shortening duration of PRP on effectiveness and cost effectiveness of PRP.

The impact of the macronutrient composition of a nutritional supplement on postprandial skeletal muscle protein synthesis in elderly

Obtain more insight in the preferred macronutrient composition of an oral nutritional supplement.

Self management and employability of workers with complaints of the arm, neck and / or shoulder

The objective of the study is to investigate the effectiveness of a combined intervention on the disabilities, self-efficacy and long-term employability of workers with complaints of the arm, neck and / or shoulder. Through a self-management program…

Abduction brace versus sling after arthroscopic cuff repair

Primary Objective: Is there reduction in pain using an abduction brace in patients undergoing arthroscopic cuff repair? Secondary Objectives: - Are there differences in function and recovery of the cuff, determined using questionnaires and echo?- Is…

Protect, The impact of a high protein diet on the preservation of muscle mass during caloric restriction in overweight middle-aged to elderly people

To investigate the effects of a high protein diet vs. standard protein diet for 12 weeks on preservation of muscle mass during caloric restriction in overweight and obese middle-aged to elderly people.

The long-term effect of the babysitterprocedure after proximal nerve injury.

Aim of this study was to assess the long term effects of the babysitter procedure in patients with proximal nerve injury.

PULSE, A protein feeding strategy to promote muscle protein anabolism in the elderly

The purpose of the study is to investigate whether a protein pulse feeding pattern increases the appearance of labeled phenylalanine in skeletal muscle tissue over a 24 h period in the elderly.

Functional treatment versus immobilization for primary patella luxations: a prospective randomized trial

Functional treatment with a brace and early physiotherapy will result in improved Kujala scores (reflecting better functional outcome with less pain) and SF-36 scores (reflecting higher quality of life) at 1 year compared with plaster immobilization…

Five year single blind effectiveness randomised actively controlled Phase III Clinical Trial in New Onset Juvenile Dermatomyositis: Steroids Treatment versus Steroids plus Cyclosporine Treatment versus Steroids plus Methotrexate Treatment

Objectives. The goals of the current protocol is therefore the natural follow-up of the objectives achieved with the previous grants and, in particular, of projects designed to discern new models for the successful conduct of clinical trials in…

Treatment of Myogenic Cranio Mandibular Dysfunction (CMD):
a prospective randomised clinical trial, comparing a mechanical stretching device (TheraBite®) with standard physiotherapy

To evaluate if a mechanical stretch device is effective in treating myogenic disturbances of the jaw joints, as compared with fysiotherapy.

Effectiveness of www.SnelBeter.nl: activating occupational care on-line in employees with sickness absence due to back or neck pain.

The purpose of this study is to investigate the effectiveness of a website.If the results indicate that the website is effective, the website may be implemented on a large scale. With the use of an effective website, companies will receive better…

Effectiveness of treatment for chronic tension headache by the general practitioner or manual therapist: pilot study for a randomized clinical trial

The objective of this pilot study is to test the feasiblity of all procedures of the RCT. The aim of the final study is to investigate the short term and long term effects of manual therapy on the frequency of headache and the use of pain medication…

No Use is Disuse: what can we gain upon functionality with exercise in boys with Duchenne Muscular Dystrophy (DMD)?

The primary objective of this project is to contribute to the knowledge of the optimal medical care of DMD patients with regard to the optimal level of physical activity by examining the effects of training primarily upon muscle endurance and/or the…

The effects of statins on skeletal muscle mitochondria:a pilot study?

Primary Objectives: To investigate whether differences exist in the mitochondrial energy generating capacity of skeletal muscle of statin users with SAMS compared to statin users without SAMS and controls (non-statin users).Secondary objectives:2A.…