13 results
In this study we aim to investigate the presence of CAN in diabetic patients scheduled for elective major abdominal and thoracic surgery and its relation with perioperative hemodynamic changes.
Are changes in cognitive functioning related to structural changes in the brain in patients with type 1 diabetes mellitus. How are these changes related to diabetic complications like duration of chronic hypoglycaemia, disease duration and presence…
The primary objectives are defined according to a hierarchical design: i) to tailor and apply multi-parametric, functional MRI techniques to identify cerebral abnormalities (cerebral biomarkers) in DM2 and MetS; ii) to investigate which cerebral…
The aim of this study is to investigate if changes in vascular compliance in children with type 1 diabetes are related to endothelial markers and to changes in skin AGE and to investigate whether patients at risk to develop cardiovascular disease…
1) Prevalence of celiac disease in a Dutch cohort of adult type 1 diabetes patients. 2) Investigation of the long term complications of type 1 diabetes patients with concomitant celiac disease
To investigate whether SAF is elevated in GDM versus non-diabetic pregnancy To investigate whther SAF levels change during the course of normal and GDM pregnancy To investigate if SAF is related to other parameters of hyperglycemia (HbA1c, self…
To study the effect of transient high blood glucose level on the brachial artery FMD response, and to determine the reproducibility of the measurements and observed effect.
It is therefore planned to study pain perception in peripheral neuropathy in the context of positive and negative emotional stimulation. Although there is a recent plea for the study of emotional modulation of pain, only one study has as yet done so…
Main study:Primary objective: What are the long-term effects (i.e. after 8-week drug exposure) of the GLP-1RA versus a single dose prandial insulin onrenal hemodynamics (glomerular filtration rate/ effective renal plasma flow in basal insulin-…
Primary Objective: To prospectively compare outcomes of subjects with diabetic foot osteomyelitis treated with antibiotics targeted at culture results from bone biopsy (intervention group) versus therapy targeted at ulcer bed biopsy culture results…
Several observational studies have been published evaluating DECTA for imaging of the lower legs, comparing this technique with conventional CTA. However, to the best of our knowledge, no randomised controlled trial has been conducted comparing both…
Primary Objective:To investigate whether arterial microcalcification (18F-NaF-PET detected) and macrocalcification (CT detected) are increased in patients with T2D who have macroalbuminuria as compared to patients with normoalbuminuria.Secondary…
This study aims to better diagnose cardiomyopathy in the increasing high-risk populations of chronic hypertension, type two diabetes mellitus, and obesity/overweight by providing gender specific cardiac MRI cut-off values for cardiac volumes,…