14 results
The aim of this study is to compare a reduced follow-up schedule of 4 visits among low-risk, early-stage endometrial cancer survivors, with the schedule according to the current Dutch guideline that includes 10 to 13 visits, on:Primary outcomes:1.…
Objective: The primary goal of the current study is to study the immunogenicity and safety of HPV vaccination in patients with an autoimmune disease. Based on retrospective analysis with other vaccines we hypothesize that patients with autoimmune…
The objective of the MINI-trial is to compare the clinical effectiveness, quality of life, and cost-effectiveness of uterine artery embolisation (UAE) to MR guided focused ultrasound (MRgFUS) in pre- or perimenopausal women with symptomatic uterine…
In order to confirm and externally validate the novel panel of genes identified in our study (06/101/K) to be significantly predictive of recurrent implantation failure, we will recruit 50 additional subjects treated by IVF who have undergone at…
Genetic analysis of the familial inheritance pattern of the COL3A1 2209G>A polymorphism.
To determine the optimal moment to start bladder training after vaginal prolapse surgery with anterior colporrhaphy.
To evaluate the duration of admission, feasibility, patient satisfaction and complication rate of vNOTES hysterectomy with BSO and compare it with laparoscopic hysterectomy with BSO in case of clinical stage 1 low grade endometrial cancer.
To determine the long-term (cost)effectiveness of Magnetic Resonance image guided High Intensity Focused Ultrasound (MR-HIFU) compared to standard (minimally) invasive fibroid care in-cluding UAE, myomectomy and hysterectomy.
The ultimate objective is to optimize pessary treatment for all patients with pelvic organ prolapse (POP). To reach this goal, we need to learn more about the mechanisms behind success and failure of pessary treatment. Previous research suggested…
Investigation of pelvic blood circulation by MRI in women with a gynaecological cancer who will have curative radiotherapy with or without weekly HT for inoperable pelvic tumours.
Current performance of biomarker signatures for non-invasive diagnosis, based on endometrial and blood samples combined with an algorithm, are the following (determined during previous studies): Sensitivity Specificity PPV NPV EndoSearch…
The primary objective of this phase 2 study in patients with advanced endometrial cancer is to compare the clinical efficacy of MLN0128 + weekly paclitaxel to weekly paclitaxel alone in second- or third-line treatment of advanced, recurrent, or…
What is the effectiveness and cost-effectiveness of surgical treatment of women suffering from pain due to an endometrioma when compared to treatment with medication?
The use of an interactive web-based Decision Aid reduces decisional conflict and increases patient satisfaction with information and care.