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Supplementation of Vigantol oil versus placebo as Add-on in patients with relapsing remitting multiple sclerosis receiving Rebif treatment (immune modulating effects of vitamin D3)

The primary objective of this study is to assess whether the CD4+ T cell compartment displays a less pro-inflammatory profile in patients which are supplemented for the SOLAR study with high doses of vitamin D3 when compared to patients which are…

Efficacy of client-centred occupational therapy in patients with multiple sclerosis: a cluster-randomized trial

The main research question of this study is:Is client-centred occupational therapy according to the Occupational Performance Process Model more effective than usual-care occuaptional therapy in patients with multiple sclerosis?

A PHASE III MULTICENTER, RANDOMIZED, DOUBLE-BLIND, DOUBLE-DUMMY, PARALLEL-GROUP STUDY TO EVALUATE THE EFFICACY AND SAFETY OF FENEBRUTINIB COMPARED WITH TERIFLUNOMIDE IN ADULT PATIENTS WITH RELAPSING MULTIPLE SCLEROSIS

The goal of the fenebrutinib development program in MS is to evaluate the benefits and risks of fenebrutinib treatment across the spectrum of patients with MS. Based on the existing toxicology, pharmacology, and clinical experience with fenebrutinib…

A PHASE IIIB MULTICENTER, RANDOMIZED, DOUBLE-BLIND, CONTROLLED STUDY TO EVALUATE THE EFFICACY, SAFETY AND PHARMACOKINETICS OF A HIGHER DOSE OF OCRELIZUMAB IN ADULTS WITH RELAPSING MULTIPLE SCLEROSIS

This study will evaluate the efficacy, safety, and pharmacokinetics of a higher dose of ocrelizumab compared with the approved dose of ocrelizumab in patients with relapsing forms of multiple sclerosis.