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Multi Sensory Stimulation And Priming (MuSSAP) in infants (4-12 months of age) at risk of developing Unilateral Cerebral Palsy (UCP).

Primary objective:The following hypothesis will be tested:MuSSAP in infants 4-12 months of age with diagnosed unilateral cerebral damage, is a feasible protocol and results in an enhanced motor development as compared to Intensive Usual Care (Upper…

TOAST-CP: Task-Oriented Arm Strength Training in children with Cerebral Palsy

The goal of the study is to enhance the participation in daily life of children with CP, by increasing their independent use of the upper limb performing daily life activities. By training the task oriented strength in daily life activities…

1) Target temperature management 33°C versus 36°C after out-of-hospital cardiac arrest,
a randomised, parallel groups, assessor blinded clinical trial
2) Target Temperature Management After Cardiac Arrest

Primary objective: To evaluate whether there is a difference in all-cause mortality at 180 days or longer with a target temperature management at 33°C compared to a target temperature of 36°C, in patients unconscious after out-of-hospital OHCA.…

Forced use therapy in the piratsgroup to improve upper limb activities in children with Cerebral Palsy:
An approach in a meaningful setting with play-based occupational therapy

The development of an attractive child centred intervention based on the forced use perspective, to study the effects regarding the following question:Is a period of 6 weeks Forced Use of the more affected upper limb (I) for children with Cerebral…

ON-SCENE Initiation of Extracorporeal CardioPulmonary Resuscitation During Refractory Out-of-Hospital Cardiac Arrest

In this study, we aim to improve survival to hospital discharge and costs/QALY in young patients with OHCA by decreasing the time in cardiac arrest by initiating ECPR on scene.

Targeted hypothermia vs. targeted normothermia after out-of-hospital cardiac arrest, a randomised clinical trial

We designed the study to test the hypothesis that post-ischaemic hypothermia, when compared tonormothermia and early treatment of fever, decreases mortality and improves neurologic functionin unconscious adults after out-of-hospital cardiac arrest.…

TAME Cardiac Arrest Trial. Targeted Therapeutic Mild Hypercapnia After Resuscitated Cardiac Arrest: A Phase III Multi-Centre Randomised Controlled Trial

The primary objective of this study is to determine whether targeted therapeutic mild hypercapnia (TTMH) improves neurological outcome at 6 months compared to standard care (targeted normocapnia) (TN).

Een nieuwe functionele loopvaardigheidstraining voor kinderen en adolescenten met Cerebrale Parese om het aanpassingsvermogen van het lopen te verbeteren: een exploratieve studie

The main objective of this exploratory study it to determine the effectiveness of a 5-week functional gait training on the C-mill to improve gait adaptability in children and adolescents with CP. t The intervention will also be evaluated on activity…