Search for a trial

Cervical radicular pain: A randomised controlled trial comparing percutaneous plasma discectomy and anterior cervical discectomy.

The aim of this study is to compare the effects of anterior cervical discectomy versus percutaneous plasma discectomy on pain, on global perceived effect, functional status and health-related quality of life in a group of patients with cervical…

Dexmedetomidine versus propofol in the awake implantation of a neuromodulative system.

The purpose of this study is to observe the usability of dexmedetomidine compared to the standard therapy (propofol) and to determine the overall satisfaction of the patient.

Interbody fusion in the treatment of cervicobrachial syndrome; a prospective trial of porous titanium cervical cages.

Documentation of the patients' functional recovery and quantification of fusion after implantation of 3-D trabecular titanium cages on the short and long term. These data will be compared with the recently performed randomized CASCADE trial on…

Step-down versus step-up analgesics in patients with (sub)acute sciatica in primary care

Primary Objective:What is the effectiveness of immediate opioid pain medication (followed by step-down) versus step-up pain medication within the treatment according general practitioners* clinical guideline in patients with (sub)acute sciatica,…

The effects of hybrid cycle exercise training in inactive people with a chronic spinal cord injury.

The primary objective is to evaluate the short- and long-term effectiveness of a hybrid cycle training program on physical capacity, active lifestyle, participation, and quality of life among a group of inactive individuals with a chronic SCI.…

The effect of 16-week low-intensity wheelchair training on functions, activities, and participation in inactive people with a spinal cord injury.

The primary objective is to evaluate the effectiveness of low-intensity hand rim wheelchair exercise training on physical capacity, daily (wheelchair) functioning, participation and quality of life in people with a spinal cord injury. Furthermore,…

Percutaneous Cervical Nucleoplasty vs. Pulsed Radio Frequency in patients with contained cervical disc herniation; a double-blind randomized clinical trial

To investigate which technique is the most effective in terms of pain relief on short term in patients with contained cervical disc herniation: PCN or PRF?

Cervical spine movement, before and after anterior cervical discectomy (ACD).
ACD, pure intervertebral discectomy (1) compared to intervertebral discectomy followed by implantation of an intervertebral disc prosthesis (2) in patients with a radicular syndrome. A randomised study

Objective of the study is to verify whether the movement pattern after anterior cervical discectomy normalises, in case of implantation of a cervical disc prosthesis.

Promoting physical activity in individuals with spinal cord injury

The general objective of this project is to evaluate, for persons with a SCI, on the short and long term, the added value of a behavioural focused intervention, on top of a physical exercise intervention, on the level of everyday physical activity.…

Cost-effectiveness of nerve root decompression according to Gill versus instrumented fusion in the treatment of spondylolytic spondylolisthesis; a multicenter prospective randomised trial.

The Sciatica-Gill trial is a randomised cost-effective study about nerve root decompression according to Gill versus instrumented fusion in the treatment of patients with radicular legpain or neurogenic claudication due to spondylolytic…

Intrathecal methylprednisolone for intractable postherpetic neuralgia.

To measure the effectiveness of intrathecal methylprednisolone and lidocaine on reducing PHN. Measurement of mthylprednisolone concentrations in cerebrospinal fluid (Part I only).

Intrathecal methylprednisolone for intractable postherpetic neuralgia.

To measure the effectiveness of intrathecal methylprednisolone and lidocaine on reducing postherpetic neuralgia. Measurement of intrathecal methylprednisolone concentrations.

Multidisciplinary behavioural program for coping with chronic neuropathic pain following spinal cord injury.

To evaluate a group treatment program to stimulate effective coping with chronic neuropathic pain following spinal cord injury.

New training modules aimed at improving upper extremity skilled performance in persons with a cervical spinal cord injury

The aim of the study is to develop and evaluate a specific client centred task-oriented training module for upper extremity skilled performance in persons with C-SCI.The research questions are:1. Does an 8-weeks client-centred task-oriented training…

Transforaminal epidural corticosteroïds versus shortacting anesthetic in patients with sciatica: a randomized prospective trial

The goal is to find answer to the question: do epidural injections with corticosteroids in patients with sciatica have a positive effect on pain, absenteeism from work and number of operations compared to standard care (pain medication only).

Cost-effectiveness of minimal invasive spinal fusion compared to open fusion for patients with spinal stenosis with neurogenic claudication or radicular leg pain.

What is the cost-effectiveness of minimal invasive posterior lumbar interbody fusion in spinal stenosis patients, compared to the standard open fusion?

The use of direct nerve visualisation with the Evotouch/7starscope compared to the conventional fluoroscopy technique for transforaminal epidural injection.

We hypothesize that using the Evotouch/7stascope, ultrasound guided TFEI procedures are non-inferior to the golden standard with fluoroscopy, which means correct placement of the needle within the neuroforamen without intravascular positioning.

Efficacy of the Myosuit for increasing daily life gait performance in the home and community setting and gait capacity in people with incomplete spinal cord injury

Part A:The primary objective is to test the efficacy of the Myosuit, a soft exosuit, for increasing daily life gait performance in the home and community setting in people with iSCI. Secondary, the efficacy of the Myosuit program on gait capacity…

Clinical assessment of upper extremity performance in individuals with spinal cord injury using the LIFT System to deliver non-invasive electrical spinal stimulation (ARC Therapy)

Safety: To provide confirmatory evidence that use of the LIFT System, inclusive of all components and accessories, is safe.Effectiveness: To provide confirmatory evidence that use of the LIFT System provides an effective treatment for the…

Handheld iOS-based spinal navigation versus computer tomography-based image guided navigation in the placement of thoracolumbar pedicle screws; protocol of a randomized controlled trial

The aim of the study is to determine the accuracy of pedicle screw placement when using the iNav navigation tool compared with the established computertomography based navigation.