70 results
To collect maternal blood during the 2nd half of pregnany, in combination with clinical data and data on pregnancy outcome.
Our objective is to test the following hypotheses : - Hypothesis 1 (part 1 of the study): The stress reduction intervention has beneficial effects on subjective maternal emotional well-being, on objective maternal stress system measures (i.e., HPA-…
The following hypotheses will be tested:Hypothese a: Remifentanil PCA gives a better labour satisfaction than pethidine/meperidine i.m.Hypothese b: Remifentanil PCA gives a better pain-relief during labour, than pethidine/meperidine intramuscularly.…
The main objective of this study is compare the analgesic efficacy and safety of remifentanil, administered as patient-controlled analgesia (PCA), with epidural analgesia.
Primary Objectives: To prospectively investigate the changes in cardiac parameters (echocardiography, NT-pro-BNP) and uteroplacental flow (pulsatility index, diastolic notching) during/after pregnancy in women with CHD and compare these changes with…
The aim of this project is to investigate whether a first trimester model of 3D placental volume, 3D power Doppler measurement of the placental vascularization and/ or serum levels of PAPP-A, PlGF, PP-13, PAI, Ang-2, sFlt and SEng can predict early…
The relationships between emotional complaints of the mothers during pregnancy and the self regulation capacities, temperament, mental and motor development of the children are studied, taking into account the influence of the father, that could be…
The main objective of this study is to compare changes in maternal temperature and oxygen saturation in patients receiving remifentanil, administered intravenous patient-controlled, with those of epidural analgesia.
The objective of this study is to test the hypothesis that healthy obese pregnant women at increased risk for obesity-related pregnancy complications can be identified by a subgroup-specific screening program at twelve weeks amenorrhea.
Primary objective:To demonstrate elevated numbers of CEC in clinically symptomatic patients with severe preeclampsia.Secondary objectives:- To analyze the relation of CEC levels with organ damage and dysfunction. - To analyze the relation of CEC…
To compare Remifentanil PCA with epidural anesthesia among healthy nulligravidia during labor.
The primary endpoint will be descriptive histology on placental bed biopsies and placenta in healthy pregnant women or women with preeclampsia and/or IUGR in need of caesarean section. In particular, the study will aim to find the degree of…
In this project we hypothesize that recurrent pregnancy miscarriages is an issue stemming from both the female as the male. The overall aim is to elucidate paternal factors associated with RPL (A) and to assess the predictive value of these factors…
Primary Objective:Delineate the differences in cellular composition and function at the maternal-fetal interface in patients with SLE compared to healthy women Secondary Objectives:- Establish a novel in-vitro model to study cell-cell interaction at…
To compare the efficacy, side effects and therapy compliance of intermittent (three times a week) versus daily oral iron supplementation for anaemia in pregnancy attributed to iron deficiency.
The objective of this pilot study is to get a preliminary understanding of the amniotomy-to-delivery interval, patient experience and risks by awaiting spontaneous contractions after amniotomy. Simultaneously we*ll be able to evaluate the process of…
Primary Objective: analyse the effect of maternal BMI on levels of macrophage cell and monocyte subsets in decidual tissue and maternal blood. Secondary Objective: analyse differences in the effect of maternal blood stimulation with conditioned…
To investigate whether discontinuation of Syntocinon® infusion after the onset of active labour decreases caesarean section rates compared to usual care; continuation of oxytocin until the baby and placenta is born.
The primary objective of this study is to assess the effectiveness of myo-inositol supplementation to prevent pregnancy complications in women with PCOS. Secondary objectives are to evaluate the impact of supplementation on maternal (mental) and…
To assess embryonic, foetal and placental growth trajectories by serial assessments of sizes and volumes and foetal morphology during the first, second and third trimester of pregnancy with the aim to examine whether BS influences embryonic growth…