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Fluids in mechanically ventilated children with acute infectious lung disease: how dry should they be?

This research project aims to determine the feasibility of setting up a randomized controlled trial to study the effects of different fluid management protocols on the outcome of mechanically ventilated pediatric patients with acute infectious lung…

Treatment in patients with recurrent infections and IgG Subclass Deficiency, and/or Deficient Anti-Polysaccharide Antibody Response.

The primary objective of the study is to compare the efficacy of intravenous immunoglobulin product with the efficacy of antibiotic treatment in patients with recurrent respiratory infections and IgG-subclass deficiency and/or selective anti-…

Routine manual hyperinflation versus on demand manual hyperinflation in intubated and mechanically ventilated post*cardiothoracic surgery patients
* A randomized controlled trial *

To compare a *routine* MH strategy with an *on demand* MH strategy in cardiothoracic surgery patients with respect to post*extubation SpO2 and FRC.

An open-label pilot study on the effects of trivalent inactivated influenza vaccination (Influvac®) in rheumatoid arthritis patients treated with rituximab

In this pilot study patients treated with a single course of rituximab or treated with multiple courses of rituximab, matched RA controls treated with methotrexate and healthy controls will be included in order to answer the following questions:1.…

Spinal Muscular Atrophy Randomized Controlled Trial on Cough Techniques
(Patient tailored airway clearance in patients with Spinal Muscular Atrophy: a randomized controlled trial comparing air stacking and mechanical insufflation-exsufflation.)

The aim of this study is to compare the effect of twice daily MI-E to twice daily AS with MAC on increase of PECF in patients with SMA with weak cough over a period of 3 years.