12 results
Primary Objective: (diagnostic)• Does MRI detect structural changes of haemophilic arthropathy in knees and ankles undetected by the Pettersson score and HJHS? (Research question 1 a & b)Secondary Objective(s): (prognostic)• Can MRI predict…
The main object is to evaluate the validity of a diagnostic screening package for bleeding tendency consisting of point-of-care devices when compared with the gold standard for bleeding tendency diagnosis.Other objects which will be investigated are…
To investigate the functionality of the hemostatic system in patients at one year after OLT. Specifically, we will investigate the function of primary hemostasis (i.e., blood platelets), secondary hemostasis (i.e, the mechanisms responsible for…
Objective:The hypothesis of this study is that laboratory markers for blood coagulation, platelet activity and inflammation may help to identify patients at risk for a recurrent cardiovascular event after ACS. Secondary, we expect to find…
Primary Objective: The primary objective is to investigate the effect of hypoxia on blood coagulation using different techniques, among others the very sensitive TG assay in whole blood and plasma.Secondary Objective: The secondary objective is to…
to determine the immediate effects of alcohol consumption in healthy volunteers on haemostasis and to evaluate the differences of artificially alcoholised blood and *naturally*, via oral uptake alcoholised blood on haemostasis as measured by…
This study has been transitioned to CTIS with ID 2024-514073-22-01 check the CTIS register for the current data. To investigate differences in coagulation between (Omniplasma) and FFP in paediatric cardiac patients, who are undergoing cardiac…
The primary objective of this study is: to develop a blood vessel-on-chip model that mimics hypercoagulability in patients with COVID-19. The secondary objective is: to evaluate the efficacy of agents that inhibit COVID-19-related hypercoagulability…
Before routinely starting collection of blood with these devices several objectives need to be addressed. A) Is there a difference in coagulation activation parameters between blood collected by venous phlebotomy, finger prick capillary blood and…
The primary objective of this study is to demonstrate that the EnzySystem HemA version A can record TG and quantify FVIII activity levels within a time frame of 60 min in fresh whole blood samples of healthy volunteers and patients with hemophilia A…
Is it possible to detect prothrombotic states via the "calibrated automated thrombogram" in patients that endured CVST, who did no show deviations in the prothrombin time/activated partial thromboplastin time? Secondary, we will…
The primary objective of this study is to investigate the additive value of new diagnostic tests to categorize patients with currently unexplained bleeding in order to refine therapeutic interventions.