1251 results
To evaluate the effectiveness of eccentric calf muscle exercise therapy compared to strength training of the upper extremities (control group) in patients with chronic midportion Achilles tendinopathy.
The primary aim of this split-mouth randomized clinical trial is to assess accuracy of bracket positioning of a fully digital IDB workflow compared to a DBB workflow, with IDB bracket planning serving as reference for both methods. The secondary…
- Six weeks of ESM combined with personalized feedback sessions, compared with treatment as usual (TAU), leads to a stronger reduction in fatigue symptoms (primary outcome clinical effectiveness). - This intervention also leads to improvements in…
Both interventions (GRAIL training & endurance and strength training (control intervention)) will result in an increase in gait speed, functional walking ability and social participation. However, the GRAIL training will result in larger…
Renal artery denervation (RDN) on top of pulmonary vein isolation (PVI) will improve the success of ablative therapy for patients who have paroxysmal and/or persistent atrial fibrillation, with out of range hypertension (systolic >140 mmHg or…
The proportion of successful patients, defined as an improvement in LARS category, will be 25% larger in the experimental group than in the control group (in which 10 % improvement is assumed).
This multicentre randomised controlled trial aims to investigate whether PoCUS can be used as an adjunct to improve first attempt success rate in closed reductions of displaced distal radial fractures in adults in the ED.
Purpose is to show that multi-electrode ablation is not inferior to irrigated single tip catheter ablation guided by 3-D mapping to treat paroxysmal atrial fibrillation.
To assess the bioequivalence of two marketed formulations of ribavirin (ribavirin solution and capsules).
To reduce the extent of healthy breast tissue resection by US-guided surgery for palpable tumours compared to traditional palpation-guided surgery, without compromising oncological principles. To improve cosmetic outcomes and quality of life by US-…
To evaluate the effectiveness of bilateral implantation over unilateral implantation in children with severe-to-profound sensorineural hearing loss. Furthermore with this study we will investigate whether simultaneous bilateral implantation is…
The objective of this pilot study is to evaluate the impact of the FreeStyle InsuLinx on glycaemic control.
The primary aim of the trial is to assess what the optimal treatment regimen for acetylsalicylic acid, a statin and two BP-lowering agents is (administered as in regular care in individual agents, a fixed-dose combination pill administered in the…
The aim of this study is to find a succesful treatment for functional abdominal pain in children and at the same time improve the quality of life of these children. A second aim is to reduce the hospital visits and with that the costs.
Primary Objective: Our main goal is to determine whether dislocated distal radius fractures immobilized in dorsoflexion gives a better functional outcome in comparison to immobilisation with the wrist in palmarflexion. For this we will use the quick…
The primary objective of this study is to test the virucidal efficacy of two alcohol based hand disinfectants (according prEN 12791) against murine norovirus 1 (MNV1) and human noroviruses (G1.4 and GII.4) on artificially contaminated hands. The…
Study 1: Examine how interparental and parent-child relationships in families who have experienced CSA differ from interparental and parent-child relationships in families who have not experienced CSA, and how these relational effects are related to…
The main objective is to analyse whether or not active forward flexion of the shoulder six months after non-operative treatment of a proximal humerus fracture is better when physical therapy is initiated directly (within 3 weeks after injury and…
To compare the overall survival of ipilimumab monotherapy at doses of 3 mg/kg versus 10 mg/kg in subjects with previously treated or untreated unresectable Stage III or Stage IV melanoma
The aim of this study is to objectify nipple-areola complex sensitivity in women who underwent unilateral or bilateral prophylactic NSM in Erasmus MC-Daniel den Hoed Cancer Center and their satisfaction with this operation, compared to healthy women…