20 results
Primary objectives of INTACT III are:1) to prospectively compare the efficacy of Sacral Nerve Stimulation (SNS) with BOTOX® 100 U related to the Patient Perception of Bladder Condition (PPBC) questionnaire (Coyne 2006) and the reduction of urinary…
Our proposed randomized controlled trial is the first making this head-to-head comparison in a *real life* primary care setting in the Netherlands. The primary research question is: does a 12-week combination therapy of open label varenicline and…
Primary ObjectiveTo evaluate the effect of a tailored behavioral change intervention comprising CBT and physical activity on participation (as measured by the DM1-Activ scale) for severely fatigued patients with myotonic dystrophy type 1 compared to…
Reduction of ICD/CRT-D follow-up by telemonitoring in a feasible way.
The primary aim of the study is to evaluate the cost-effectiveness of a collaborative care model for major depressive disorder in the occupational health setting.
The most important objectives in this study are: (1) the development of a standardized method to instruct and train patients how to use a CCTV; (2) the effectiveness of this instruction and training program in the use of a CCTV and (3) the…
to study postoperative oxygenation patterns in patients with OSA during the first three postoperative nights and 6 weeks after operation. The results of these observations will be compared to other patients groups with known respiratory compromise…
The cost-effectiveness of multidisciplinary management of Tinnitus at a specialised Tinnitus Center.
The main objective of this study proposal is to examine the effectiveness, costs, and cost-effectiveness of an integral treatment provided by a specialised tinnitus center.
What is the normal stool frequency among premature and full term neonates?What is the normal colour of stools of the neonate?What is the normal consistency and amount of stools?What is the normal colonic transit time of premature and full term born…
The goal if this study is to find out what the most effective source of the (social) comparison information is when it comes to increasing quality of life and decreasing negative emotions.
To demonstrate that FS laser aided keratoplasty for KC is superior to MALK.
The main study objective is to examine the effect of the PTWD program on glycaemic control of lower-educated participants with T2D. The secondary objectives include the effect on medication use, use of care and T2D self-management behaviours. We…
Objective: The primary objective is to assess the effects of continuous monitoring of patients in the acute admission ward (AAW) with a wearable sensor on the percentage of patients who can be discharged home. Secondary objectives are to assess the…
Our main objective is to conduct a pilot study testing the applicability and face/external validity of the battery in a young-onset PD cohort, alongside age-matched healthy controls. We aim to gain deeper insights into the complex interrelationships…
The Check@Home consortium aims to set up a roadmap and infrastructure for a (cost-)effective program to early detect atrial fibrillation and chronic kidney disease (defined by elevated albuminuria) in the general population. Furthermore, the project…
To assess whether adjuvant chemotherapy can be safely omitted in patients with pathological stage I (pT1a/b/cN0) TNBC and a high sTIL score (defined as >=50% for patients <40 years at the time of TNBC diagnosis; >=75% for…
Aim: to develop, implement and evaluate COMBO to improve SDM during the treatment trajectory of TC patients in situations when clear cut recommendations cannot be made either because the benefits closely balance with risks, or because this balance…
The primary objective of the MENTUPP research project is to improve mental health in the workplace by developing, implementing and evaluating the effectiveness of a multicomponent intervention (MENTUPP) targeting mental health difficulties (non-…
We hypothesize that the follow-up and aftercare of prostate cancer in the Netherlands can be led by the GP. We hypothesize that GP-led recurrence detection programme leads to at least equal detection of recurrences as the current follow-up in…
The main objective of this study is to assess the feasibility, safety and (cost-)effectiveness of the HOME-ART intervention in comparison to regular hospital admission in patients with CA-ARTI.